Transforming growth factor beta-induced (TGFBI) corneal dystrophies are a group of
inherited progressive corneal diseases. Accumulation of transforming growth factor beta …

Transforming growth factor-β-induced protein (TGFBIp), an extracellular matrix protein, is the
second most abundant protein in the corneal stroma. In this review, we summarize the …

TGFBI p is a constituent of the extracellular matrix in many human tissues including the
cornea, where it is one of the most abundant proteins expressed. TGFBI p interacts with …

Purpose To provide a brief summary and comparison of the most recent literature on
available and theorized treatment modalities for classic lattice corneal dystrophy (LCD). This …

Purpose: Transforming growth factor beta-induced (TGFBI)–related dystrophies constitute
the most common heritable forms of corneal dystrophy worldwide. However, other than the …

TGFBI-associated corneal dystrophies are inherited disorders caused by TGFBI gene
variants that promote deposition of mutant protein (TGFBIp) as insoluble aggregates in the …

The pentraxin serum amyloid P component (SAP) is secreted by the liver and found in
plasma at a concentration of approximately 30 mg/L. SAP is a 25 kDa homopentamer known …

Amyloidosis is a disorder characterized by extracellular fibrillar deposits of misfolded
proteins. The amyloid deposits commonly contain several non-fibrillar proteins as amyloid …

The serine protease high-temperature requirement protein A1 (HtrA1) is associated with
protein-misfolding disorders such as Alzheimer's disease and transforming growth factor β …

Drugs that can treat one disease may either be detrimental or beneficial toward another due
to possible cross-interactions. Therefore, care in choosing a suitable drug for patients with …