Pathogenesis of Helicobacter pylori Infection

JG Kusters, AHM Van Vliet… - Clinical microbiology …, 2006 - Am Soc Microbiol
Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …

Host-bacterial interactions in Helicobacter pylori infection

MR Amieva, EM El–Omar - Gastroenterology, 2008 - Elsevier
Helicobacter pylori are spiral-shaped gram-negative bacteria with polar flagella that live
near the surface of the human gastric mucosa. They have evolved intricate mechanisms to …

Cancer and inflammation: promise for biologic therapy

S Demaria, E Pikarsky, M Karin… - Journal of …, 2010 - journals.lww.com
Cancers often arise as the end stage of inflammation in adults, but not in children. As such
there is a complex interplay between host immune cells during neoplastic development, with …

Role of Innate Immunity in Helicobacter pylori-Induced Gastric Malignancy

RM Peek Jr, C Fiske, KT Wilson - Physiological reviews, 2010 - journals.physiology.org
Helicobacter pylori colonizes the majority of persons worldwide, and the ensuing gastric
inflammatory response is the strongest singular risk factor for peptic ulceration and gastric …

An Overview of Helicobacter pylori Infection

R FitzGerald, SM Smith - Helicobacter pylori, 2021 - Springer
Helicobacter pylori (H. pylori) represents one of the most widespread bacterial infections
globally. Infection causes chronic gastritis and increases the risk of peptic ulcer disease …

Helicobacter pylori Persistence: an Overview of Interactions between H. pylori and Host Immune Defenses

HMS Algood, TL Cover - Clinical microbiology reviews, 2006 - Am Soc Microbiol
Helicobacter pylori is a gram-negative bacterium that persistently colonizes more than half of
the global human population. In order to successfully colonize the human stomach, H. pylori …

Activation of mast cells by double-stranded RNA: evidence for activation through Toll-like receptor 3

M Kulka, L Alexopoulou, RA Flavell… - Journal of Allergy and …, 2004 - Elsevier
BACKGROUND: Although mast cells (MCs) have been clearly implicated in innate immune
responses involving bacteria, their ability to respond to viral infection is less clear …

Helicobacter pylori: A Contemporary Perspective on Pathogenesis, Diagnosis and Treatment Strategies

A Ali, KI AlHussaini - Microorganisms, 2024 - mdpi.com
Helicobacter pylori (H. pylori) is a Gram-negative bacterium that colonizes the gastric
mucosa and is associated with various gastrointestinal disorders. H. pylori is a pervasive …

Pattern-recognition receptors and gastric cancer

N Castaño-Rodríguez, NO Kaakoush… - Frontiers in …, 2014 - frontiersin.org
Chronic inflammation has been associated with an increased risk of several human
malignancies, a classic example being gastric adenocarcinoma (GC). Development of GC is …

The Possible Role of Helicobacter pylori in Gastric Cancer and Its Management

KO Alfarouk, AHH Bashir, AN Aljarbou… - Frontiers in …, 2019 - frontiersin.org
Helicobacter pylori (HP) is a facultative anaerobic bacterium. HP is a normal flora having
immuno-modulating properties. This bacterium is an example of a microorganism inducing …