Oxidatively induced DNA damage and its repair in cancer

M Dizdaroglu - Mutation Research/Reviews in Mutation Research, 2015 - Elsevier
Oxidatively induced DNA damage is caused in living organisms by endogenous and
exogenous reactive species. DNA lesions resulting from this type of damage are mutagenic …

Urinary biomarkers of oxidative status

D Il'yasova, P Scarbrough, I Spasojevic - Clinica chimica acta, 2012 - Elsevier
Oxidative damage produced by reactive oxygen species (ROS) has been implicated in the
etiology and pathology of many health conditions, including a large number of chronic …

[HTML][HTML] Biomarkers of nucleic acid oxidation–A summary state-of-the-art

MR Chao, MD Evans, CW Hu, Y Ji, P Møller, P Rossner… - Redox Biology, 2021 - Elsevier
Oxidatively generated damage to DNA has been implicated in the pathogenesis of a wide
variety of diseases. Increasingly, interest is also focusing upon the effects of damage to the …

8-Hydroxy-2′-deoxyguanosine as a marker of oxidative DNA damage related to occupational and environmental exposures

A Pilger, HW Rüdiger - … archives of occupational and environmental health, 2006 - Springer
Oxidative DNA damage is considered to play an important role in pathophysiological
processes, ageing and cancer. So far major interest has been on measuring 8-hydroxy-2 …

Dual-responsive carbon quantum dots for the simultaneous detection of cytosine and 5-methylcytosine interpreted by a machine learning-assisted smartphone

J Thonghlueng, S Ngernpimai… - … Applied Materials & …, 2023 - ACS Publications
DNA methylation is an epigenetic alteration that results in 5-methylcytosine (5-mC) through
the addition of a methyl group to the fifth carbon of a cytosine (C) residue. The methylation …

[HTML][HTML] Association between oxidative DNA damage and risk of colorectal cancer: sensitive determination of urinary 8-hydroxy-2′-deoxyguanosine by UPLC-MS/MS …

C Guo, X Li, R Wang, J Yu, M Ye, L Mao, S Zhang… - Scientific reports, 2016 - nature.com
Oxidative DNA damage plays crucial roles in the pathogenesis of numerous diseases
including cancer. 8-hydroxy-2′-deoxyguanosine (8-OHdG) is the most representative …

Measurement and meaning of oxidatively modified DNA lesions in urine

MS Cooke, R Olinski, S Loft… - … Biomarkers & Prevention, 2008 - AACR
Background: Oxidatively generated damage to DNA has been implicated in the
pathogenesis of a wide variety of diseases. The noninvasive assessment of such damage …

Biomarkers of oxidative stress and damage in human populations exposed to arsenic

A De Vizcaya-Ruiz, O Barbier, R Ruiz-Ramos… - … /Genetic Toxicology and …, 2009 - Elsevier
Arsenic (As) is an ubiquitous element in the environment for which the main route of human
exposure is through consumption of drinking water. Reactive oxygen species generation …

Associations of neonatal lead, cadmium, chromium and nickel co-exposure with DNA oxidative damage in an electronic waste recycling town

W Ni, Y Huang, X Wang, J Zhang, K Wu - Science of the total environment, 2014 - Elsevier
Objective This study aimed to evaluate the effects of toxic heavy metal co-exposure on DNA
oxidative damage in neonates from a primitive e-waste recycling region, Guiyu town, China …

8-Hydroxydeoxyguanosine: a new potential independent prognostic factor in breast cancer

H Sova, A Jukkola-Vuorinen, U Puistola… - British journal of …, 2010 - nature.com
Background: 8-Hydroxydeoxyguanosine (8-oxodG) is the commonly used marker of
oxidative stress-derived DNA damage. 8-OxodG formation is regulated by local antioxidant …