Inflammatory bowel disease (IBD) is a chronic, relapsing gastrointestinal (GI) disorder
characterized by intestinal inflammation. The etiology of IBD is multifactorial and results from …

Digestive system diseases arise primarily through the interplay of genetic and environmental
influences; there is an urgent need in elucidating the pathogenic mechanisms of these …

Recent progress in bovine intestinal organoid research has expanded opportunities for
creating improved in vitro models to study intestinal physiology and pathology. However, the …

A key component of efforts to identify the biological and drug-specific aspects contributing to
therapeutic failure or unexpected exposure-associated toxicity is the study of drug–intestinal …

Preclinical biomedical research is limited by the predictiveness of in vivo and in vitro models.
While in vivo models offer the most complex system for experimentation, they are also …

Sepsis is a potentially fatal condition characterized by organ dysfunction caused by an
imbalanced immune response to infection. Although an increased inflammatory response …

In this study, we isolated and cultured canine and feline 3D corneal organoids. Samples
derived from corneal limbal epithelium from one canine and one feline patient were …

As the largest internal organ, the liver is the key hub for many physiological processes.
Previous research on the liver has been mainly conducted on animal models and cell lines …

Organoids are in vitro organ-like structures that faithfully recapitulate many characteristics of
a specific organ. During the past decades, major progress has been accomplished in …

Simple Summary One Health is a concept that describes the interplay between humans,
animals, and the environment. This interaction is becoming increasingly important as …