Genetic predisposition to developmental dysplasia of the hip

E Kenanidis, NK Gkekas, A Karasmani… - The Journal of …, 2020 - Elsevier
Background The etiopathogenesis of developmental dysplasia of the hip (DDH) has not
been clarified. This systematic review evaluated current literature concerning all known …

Heterozygous LRP1 deficiency causes developmental dysplasia of the hip by impairing triradiate chondrocytes differentiation due to inhibition of autophagy

W Yan, L Zheng, X Xu, Z Hao… - Proceedings of the …, 2022 - National Acad Sciences
Developmental dysplasia of the hip (DDH) is one of the most common congenital skeletal
malformations; however, its etiology remains unclear. Here, we conducted whole-exome …

Whole exome sequencing of 28 families of Danish descent reveals novel candidate genes and pathways in developmental dysplasia of the hip

M Dembic, L van Brakel Andersen, MJ Larsen… - Molecular Genetics and …, 2023 - Springer
Developmental dysplasia of the hip (DDH) is a common condition involving instability of the
hip with multifactorial etiology. Early diagnosis and treatment are critical as undetected DDH …

[PDF][PDF] Developmental dysplasia of the hip: promoting global exchanges to enable understanding the disease and improve patient care

F Canavese, P Castañeda, J Hui, LY Li, YQ Li… - … & Traumatology: Surgery …, 2020 - Elsevier
Developmental Dysplasia of the Hip (DDH) is prevalent, affecting 1% to 3% of all infants [1];
despite this, there remains a lack of quality evidence to guide clinical practice, and even the …

Genetics of human brain evolution

EJ Vallender - Progress in Brain Research, 2019 - Elsevier
During the course of evolution the human brain has increased in size and complexity,
ultimately these differences are the result of changes at the genetic level. Identifying and …

Single-nucleus RNA and multiomics in situ pairwise sequencing reveals cellular heterogeneity of the abnormal ligamentum teres in patients with developmental …

Z Zhao, C Fan, S Wang, H Wang, H Deng, S Zeng… - Heliyon, 2024 - cell.com
Developmental dysplasia of the hip (DDH) is the most common hip deformity in pediatric
orthopedics. One of the common pathological changes in DDH is the thickening and …

The Association Between BMP-2, UQCC1 and CX3CR1 Polymorphisms and the Risk of Developmental Dysplasia of the Hip

E Gumus, E Temiz, B Sarikaya, O Yuksekdag… - Indian Journal of …, 2021 - Springer
Objective Developmental dysplasia of the hip (DDH) is a complicated skeletal disease
ranging from subluxation to complete dislocation of the hip as a result of insufficient …

[PDF][PDF] Nuove misure di outcome e variabilità genetica nell'amiloidosi ereditaria da transtiretina

E Vegezzi - 2023 - iris.unipv.it
Novel outcome measures and genetic variability in hereditary transthyretin amyloidosis Page 1
PhD in Biomedical Sciences Department of Brain and Behavioral Sciences Unit of …

PPP6R2 is a Novel Candidate Gene for Developmental Dysplasia of the Hip as Revealed by Whole Exome Sequencing of 29 Families of Danish Descent

M Dembic, L van Brakel Andersen, MJ Larsen… - 2021 - researchsquare.com
Background Developmental dysplasia of the hip (DDH) is a common condition involving
instability of the hip with multifactorial etiology. Early diagnosis and treatment are critical as …

[PDF][PDF] The Link between miR-96 Levels and the Developmental Dysplasia of the Hip.

E Gumus, E Temiz, T Demircan, B Sarikaya… - Gazi Medical …, 2022 - researchgate.net
Background: Developmental dysplasia of the hip (DDH) is a sophisticated skeletal disease
ranging from subluxation to entire dislocation of the hip as a result of missing growth of the …