Evidence on the health benefits of supplemental propolis

A Braakhuis - Nutrients, 2019 - mdpi.com
Propolis is a honey-related product with reported health benefits such as improved
immunity, lowered blood pressure, treated allergies and skin conditions. A literature review …

Revisiting Licorice as a functional food in the management of neurological disorders: bench to trend

R Sharma, RK Singla, S Banerjee, R Sharma - … & Biobehavioral Reviews, 2023 - Elsevier
Traditional and scientific evidence attribute numerous bioactivities of Licorice (Glycyrrhiza
glabra Linn.) in aging-related disorders. In this state-of-art review, an extensive search in …

[HTML][HTML] Current advances on the therapeutic potential of pinocembrin: an updated review

MH Elbatreek, I Mahdi, W Ouchari, MF Mahmoud… - Biomedicine & …, 2023 - Elsevier
Abstract Pinocembrin (5, 7-dihydroxyflavone) is a major flavonoid found in many plants,
fungi and hive products, mainly honey and propolis. Several in vitro and preclinical studies …

Pinocembrin: a novel natural compound with versatile pharmacological and biological activities

A Rasul, FM Millimouno, W Ali Eltayb… - BioMed research …, 2013 - Wiley Online Library
Pinocembrin (5, 7‐dihydroxyflavanone) is one of the primary flavonoids isolated from the
variety of plants, mainly from Pinus heartwood, Eucalyptus, Populus, Euphorbia, and …

The Nrf2/HO‐1 Axis as targets for flavanones: Neuroprotection by pinocembrin, naringenin, and Eriodictyol

S Habtemariam - Oxidative medicine and cellular longevity, 2019 - Wiley Online Library
Flavanones are a group of flavonoids that derive from their immediate chalcone precursors
through the action of chalcone isomerase enzymes. The Aromatic A and B rings, C4‐keto …

Pinocembrin protects hemorrhagic brain primarily by inhibiting toll-like receptor 4 and reducing M1 phenotype microglia

X Lan, X Han, Q Li, Q Li, Y Gao, T Cheng, J Wan… - Brain, behavior, and …, 2017 - Elsevier
Neuroinflammation is a major contributor to intracerebral hemorrhage (ICH) progression, but
no drug is currently available to reduce this response and protect against ICH-induced …

DCEO biotechnology: tools to design, construct, evaluate, and optimize the metabolic pathway for biosynthesis of chemicals

X Chen, C Gao, L Guo, G Hu, Q Luo, J Liu… - Chemical …, 2018 - ACS Publications
Chemical synthesis is a well established route for producing many chemicals on a large
scale, but some drawbacks still exist in this process, such as unstable intermediates …

Metabolic engineering of Escherichia coli for (2S)-pinocembrin production from glucose by a modular metabolic strategy

J Wu, G Du, J Zhou, J Chen - Metabolic engineering, 2013 - Elsevier
Flavonoids are valuable natural products widely used in human health and nutrition. Recent
advances in synthetic biology and metabolic engineering have yielded improved strain titers …

Polyphenols mediate neuroprotection in cerebral ischemic stroke—an update

SA Abdelsalam, K Renu, HA Zahra, BM Abdallah… - Nutrients, 2023 - mdpi.com
Stroke is one of the main causes of mortality and disability, and it is due to be included in
monetary implications on wellbeing frameworks around the world. Ischemic stroke is caused …

Advances in biosynthesis, pharmacology, and pharmacokinetics of pinocembrin, a promising natural small-molecule drug

X Shen, Y Liu, X Luo, Z Yang - Molecules, 2019 - mdpi.com
Pinocembrin is one of the most abundant flavonoids in propolis, and it may also be widely
found in a variety of plants. In addition to natural extraction, pinocembrin can be obtained by …