Mechanistically, chimeric genes result from DNA rearrangements and include parts of
preexisting normal genes combined at the genomic junction site. Some rearranged genes …

Colorectal cancer (CRC) is the third most common and second most lethal type of cancer
worldwide, presenting major health risks as well as economic costs to both people and …

Despite the high lethality of colorectal cancers (CRCs), only a limited number of genetic risk
factors are identified. The mammalian ssDNA-binding protein complex CTC1-STN1-TEN1 …

There is an increase in the incidence of early onset colorectal carcinoma (EOCRC). To
better understand if there is any difference in molecular pathogenesis of EOCRC and late …

Telomeric sequences, the structures comprised of hexanucleotide repeats and associated
proteins, play a pivotal role in chromosome end protection and preservation of genomic …

Traditional single nucleic acid assays can only detect one target while multiple nucleic acid
assays can detect multiple targets simultaneously, providing comprehensive and accurate …

Simple Summary Cancer affects millions worldwide, with gastrointestinal cancers being
notably common. This review explores the potential of telomeres and telomerase as …

Kirsten Rat Sarcoma (KRAS) is the most commonly mutated oncogene in colorectal
carcinoma (CRC). We have previously reported the interactions between microsatellite …

Simple Summary Colon cancer is one of the common cancers affecting a large number of
patients globally. In sporadic CRC, several genetic factors may play important roles such as …

Background and Objective: In sporadic colorectal carcinomas (CRC), microsatellite
instability (MSI) pathways play important roles. Previously, we showed differences in DNA …