New methods for lipid nanoparticles preparation

F Corrias, F Lai - Recent patents on drug delivery & formulation, 2011 - ingentaconnect.com
Lipid nanoparticles have attracted many researchers during recent years due to the
excellent tolerability and advantages compared to liposomes and polymeric nanoparticles …

Compositions and methods of making sustained release liquid formulations

M Tengler, P Taskey, D Lockhart… - US Patent 8,318,210, 2012 - Google Patents
4,438,150 A* 3/1984 Gantwerker et a1.......... 426/625 a dense, thixotropic solution having a
density that is at, or about, the density of the one or more microbeads comprising a …

Lipid nanoparticles as vehicles for macromolecules: nucleic acids and peptides

A del Pozo-Rodríguez, D Delgado… - Recent Patents on …, 2011 - benthamdirect.com
Traditional drug delivery systems are not efficient for peptide, protein and nucleic acid
(plasmid DNA, oligonucleotides or short interfering RNA) delivery, thereby LNP have been …

Implantable polymeric device for sustained release of buprenorphine

RA Patel, LR Bucalo - US Patent 7,736,665, 2010 - Google Patents
The present invention provides compositions, methods, and kits for treatment of opiate
addiction and pain. The invention provides a biocompatible nonerodible polymeric device …

Compounds and pharmaceutical compositions for the treatment of viral infections

D Surleraux, G Gosselin - US Patent 9,243,025, 2016 - Google Patents
DKNOJNROIXKPSJ-UJMVTGRRSA-N C# C [C@] 1 (F) C (O)[C@@ H](COP (= O)(NC (CC
(C) C) C (= O) OC) NC (CC (C) C) C (= O) OC) O [C@ H] 1N1C= NC2= C1N= C (N) NC2= O …

Sodium thiosulfate-containing pharmaceutical compositions

C Sherman, CM Smith, KR Wirtz, E Schulze - US Patent 8,496,973, 2013 - Google Patents
Provided herein are pharmaceutically acceptable sodium thiosulfate and pharmaceutical
compositions thereof. Also provided herein are methods for determining the total non …

Processes for preparing isoquinolinones and solid forms of isoquinolinones

P Ren, M Martin, P Isbester, BS Lane… - US Patent 8,809,349, 2014 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
46491229&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Antiproliferative compounds and methods of use thereof

J Hansen, MD Correa, R Raheja… - US Patent …, 2016 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
53682892&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Modifying drug release in suspensions of ionic resin systems

YV Pathak, RL McMahen, M Tengler - US Patent 8,313,770, 2012 - Google Patents
The present invention includes compositions and methods for delivering one or more unit
dosage units by modifying the release pro? le of an optionally coated drug-resin complex …

Raf kinase modulator compounds and methods of use thereof

S Abraham, SS Bhagwat, BT Campbell, Q Chao… - US Patent …, 2013 - Google Patents
2010-05-27 Assigned to AMBIT BIOSCIENCES CORP. reassignment AMBIT BIOSCIENCES
CORP. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS) …