Effect of inflammation on lacrimal gland function

D Zoukhri - Experimental eye research, 2006 - Elsevier
The lacrimal gland is the main contributor to the aqueous layer of the tear film. It secretes
proteins, electrolytes and water, which helps to nourish and protect the ocular surface …

Oral manifestations of Sjögren's syndrome

SA Mathews, BT Kurien… - Journal of dental …, 2008 - journals.sagepub.com
Sjögren's syndrome is a common autoimmune rheumatic disease. The most common
symptoms of Sjögren's syndrome are extreme tiredness, along with dry eyes …

Subgroups of Sjögren syndrome patients according to serological profiles

VK Bournia, PG Vlachoyiannopoulos - Journal of autoimmunity, 2012 - Elsevier
Sjögren Syndrome (SS) is a systemic, autoimmune disorder characterized by lymphocytic
infiltration of the exocrine glands. Different clinical associations have been described for …

A comprehensive review of autoantibodies in primary Sjögren's syndrome: clinical phenotypes and regulatory mechanisms

NC Kyriakidis, EK Kapsogeorgou, AG Tzioufas - Journal of autoimmunity, 2014 - Elsevier
Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by periepithelial
lymphocytic infiltrates in affected tissues and the production of plethora of autoantibodies …

Antimuscarinic antibodies in primary Sjögren's syndrome reversibly inhibit the mechanism of fluid secretion by human submandibular salivary acinar cells

LJ Dawson, J Stanbury, N Venn… - Arthritis & …, 2006 - Wiley Online Library
Objective. Sjögren's syndrome (SS) is an auto-immune condition affecting salivary glands,
for which a clearly defined pathogenic autoantibody has yet to be identified. Autoantibodies …

Aquaporins in salivary glands: from basic research to clinical applications

C Delporte, A Bryla, J Perret - International journal of molecular sciences, 2016 - mdpi.com
Salivary glands are involved in saliva secretion that ensures proper oral health. Aquaporins
are expressed in salivary glands and play a major role in saliva secretion. This review will …

Sjögren's syndrome—study of autoantigens and autoantibodies

JG Routsias, AG Tzioufas - Clinical reviews in allergy & immunology, 2007 - Springer
The presence of autoantibodies is the hallmark of systemic autoimmune diseases. During
the past 30 years, intense clinical and basic research have dissected the clinical value of …

Unraveling the pathophysiology of Sjogren syndrome-associated dry eye disease

CQ Nguyen, AB Peck - The ocular surface, 2009 - Elsevier
Sjogren syndrome (SS) is one of the most common autoimmune diseases. Early clinical
manifestations of SS are primarily decreased tear and saliva secretion, leading to dry eye …

Active agents, biomaterials, and technologies to improve biolubrication and strengthen soft tissues

BG Cooper, C Bordeianu, A Nazarian, BD Snyder… - Biomaterials, 2018 - Elsevier
Normal functioning of articulating tissues is required for many physiological processes
occurring across length scales from the molecular to whole organism. Lubricating …

Sjogrens syndrome—the non-apoptotic model of glandular hypofunction

LJ Dawson, PC Fox, PM Smith - Rheumatology, 2006 - academic.oup.com
The 'classical'model to explain glandular hypofunction in Sjogrens syndrome (SS) is tissue
loss secondary to immune attack mediated by a combination of apoptosis and cytotoxic cell …