Imidazole ring is an important five‐membered aromatic heterocycle widely present in natural
products and synthetic molecules. The unique structural feature of imidazole ring with …

Over the past decades, the bulk of chemists' interests have been on heterocyclic compounds
and their various derivatives as well as their applications in the pharmaceutical and …

The 1, 3, 4‐thiadiazole nucleus is one of the most important and well‐known heterocyclic
nuclei, which is a common and integral feature of a variety of natural products and medicinal …

Azole compounds are an important class of nitrogen heterocycles with electron-rich
property. This special structure endows azole-based derivatives easily bind with the …

Oxazolidinone is a five-member heterocyclic ring with several biological applications in
medicinal chemistry. Among the three possible isomers, 2-oxazolidinone is the most …

The rapid growth of serious infections caused by antibiotic resistant bacteria, especially the
nosocomial ESKAPE pathogens, has been acknowledged by Governments and scientists …

The oxazolidinones are a new and potent class of antimicrobial agents with activity mainly
against Gram-positive strains. The commercial success of linezolid, the only FDA-approved …

Abstract Three series of 1, 3-diaryl pyrazole derivatives bearing aminoguanidine or furan-2-
carbohydrazide moieties have been synthesized, characterized and evaluated for …

A series of natural berberine-derived nitroimidazoles as novel antibacterial agents were
designed, synthesized and characterized by nuclear magnetic resonance (NMR), infrared …

Novel sulfonamide-based four-component molecular hybrids as potential DNA-targeting
antimicrobial agents were developed from marketed acetanilide through convenient …