[HTML][HTML] Risk factors contributing to type 2 diabetes and recent advances in the treatment and prevention
Y Wu, Y Ding, Y Tanaka, W Zhang - International journal of medical …, 2014 - ncbi.nlm.nih.gov
Type 2 diabetes is a serious and common chronic disease resulting from a complex
inheritance-environment interaction along with other risk factors such as obesity and …
inheritance-environment interaction along with other risk factors such as obesity and …
The role of IGF2BP2, an m6A reader gene, in human metabolic diseases and cancers
J Wang, L Chen, P Qiang - Cancer cell international, 2021 - Springer
The human insulin-like growth factor 2 (IGF2) mRNA binding proteins 2 (IGF2BP2/IMP2) is
an RNA-binding protein that regulates multiple biological processes. Previously, IGF2BP2 …
an RNA-binding protein that regulates multiple biological processes. Previously, IGF2BP2 …
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown.
We conducted a multiancestry genome-wide-association meta-analysis in 521,612 …
We conducted a multiancestry genome-wide-association meta-analysis in 521,612 …
The bigger picture of FTO—the first GWAS-identified obesity gene
Single nucleotide polymorphisms (SNPs) that cluster in the first intron of fat mass and
obesity associated (FTO) gene are associated obesity traits in genome-wide association …
obesity associated (FTO) gene are associated obesity traits in genome-wide association …
Diabetes in asia
A Ramachandran, RCW Ma, C Snehalatha - The Lancet, 2010 - thelancet.com
Prevalence of type 2 diabetes has rapidly increased in native and migrant Asian
populations. Diabetes develops at a younger age in Asian populations than in white …
populations. Diabetes develops at a younger age in Asian populations than in white …
Type 2 diabetes in South Asians: similarities and differences with white Caucasian and other populations
Type 2 diabetes mellitus (T2DM) is one of the leading causes of morbidity and mortality.
While all ethnic groups are affected, the prevalence of T2DM in South Asians, both in their …
While all ethnic groups are affected, the prevalence of T2DM in South Asians, both in their …
Rare variants create synthetic genome-wide associations
Genome-wide association studies (GWAS) have now identified at least 2,000 common
variants that appear associated with common diseases or related traits (http://www. genome …
variants that appear associated with common diseases or related traits (http://www. genome …
Zinc and diabetes—clinical links and molecular mechanisms
J Jansen, W Karges, L Rink - The Journal of nutritional biochemistry, 2009 - Elsevier
Zinc is an essential trace element crucial for the function of more than 300 enzymes and it is
important for cellular processes like cell division and apoptosis. Hence, the concentration of …
important for cellular processes like cell division and apoptosis. Hence, the concentration of …
Antidiabetic effects of IGFBP2, a leptin-regulated gene
We tested whether leptin can ameliorate diabetes independent of weight loss by defining the
lowest dose at which leptin treatment of ob/ob mice reduces plasma glucose and insulin …
lowest dose at which leptin treatment of ob/ob mice reduces plasma glucose and insulin …
The elevated susceptibility to diabetes in India: an evolutionary perspective
India has rapidly become a “diabetes capital” of the world, despite maintaining high rates of
under-nutrition. Indians develop diabetes at younger age and at lower body weights than …
under-nutrition. Indians develop diabetes at younger age and at lower body weights than …