Multiple receptors contribute to the behavioral effects of indoleamine hallucinogens

AL Halberstadt, MA Geyer - Neuropharmacology, 2011 - Elsevier
Serotonergic hallucinogens produce profound changes in perception, mood, and cognition.
These drugs include phenylalkylamines such as mescaline and 2, 5-dimethoxy-4 …

Central monoamines and their role in major depression

AS Elhwuegi - Progress in Neuro-Psychopharmacology and …, 2004 - Elsevier
The role of the monoamines serotonin and noradrenaline in mental illnesses including
depression is well recognized. All antidepressant drugs in clinical use increase acutely the …

PET imaging of serotonin 1A receptor binding in depression

WC Drevets, E Frank, JC Price, DJ Kupfer, D Holt… - Biological …, 1999 - Elsevier
Background: The serotonin-1A (5HT1A) receptor system has been implicated in the
pathophysiology of major depression by postmortem studies of suicide victims and …

Brain serotonin1A receptor binding measured by positron emission tomography with [11C] WAY-100635: effects of depression and antidepressant treatment

PA Sargent, KH Kjaer, CJ Bench… - Archives of general …, 2000 - jamanetwork.com
Background Pharmacological and postmortem investigations suggest that patients with
major depressive disorder have alterations in function or density of brain serotonin 1A (5-HT …

The complex role of serotonin and 5-HT receptors in chronic pain

L Bardin - Behavioural pharmacology, 2011 - journals.lww.com
Abstract Serotonin [5-hydroxytryptamine (5-HT)] in the central nervous system and in the
periphery has long been considered to have an important role in the control of pain, for …

Increase in serotonin-1A autoreceptors in the midbrain of suicide victims with major depression—postmortem evidence for decreased serotonin activity

CA Stockmeier, LA Shapiro, GE Dilley… - Journal of …, 1998 - Soc Neuroscience
It has been hypothesized that a deficit in serotonin may be a crucial determinant in the
pathophysiology of major depression. Serotonin-1A receptors are located on serotonin cell …

Serotonin-1A receptor imaging in recurrent depression: replication and literature review

WC Drevets, ME Thase, EL Moses-Kolko, J Price… - Nuclear medicine and …, 2007 - Elsevier
INTRODUCTION: Serotonin-1A receptor (5-HT1AR) function appears to be decreased in
major depressive disorder (MDD) based on physiological responses to 5-HT1AR agonists in …

5-HT1, 5-HT2, 5-HT3 and 5-HT7 receptors and their role in the modulation of pain response in the central nervous system

JL Cortes-Altamirano… - Current …, 2018 - ingentaconnect.com
Background: The aim of this review was to identify the mechanisms by which serotonin
receptors involved at the central level are able to modulate the nociceptive response. Pain is …

The serotonergic and noradrenergic systems of the hippocampus: their interactions and the effects of antidepressant treatments

R Mongeau, P Blier, C De Montigny - Brain Research Reviews, 1997 - Elsevier
Previous reviews have well illustrated how antidepressant treatments can differentially alter
several neurotransmitter systems in various brain areas. This review focuses on the effects …

Pharmacology of antidepressants

A Frazer - Journal of Clinical Psychopharmacology, 1997 - journals.lww.com
This review covers mechanisms of action, efficacy, side effects, and toxicity of various
classes of antidepressants: tricyclic antidepressants, monoamine oxidase inhibitors, second …