Exosomes play critical roles in intercellular communication in both nearby and distant cells
in individuals and organs. Polymerase I and transcript release factor (PTRF), also known as …

Gliomas with mutant p53 occurring in 30% of glioma patients exhibit therapeutic resistance
and poor outcomes. In this study, we identify a novel mechanism through which mutant p53 …

Chemoresistance is the major obstacle to cure endometrial cancer, whereas metformin has
demonstrated sensitization to chemotherapy in endometrial cancer. A novel finding states …

Recent years have seen considerable progress in understanding the biochemistry of cancer.
For example, more significance is now assigned to the tumor microenvironment, especially …

Numerous genetic pathways associated with glioblastoma development have been
identified. In this study, we investigated the prognostic significance of IDH1 and ATRX …

Abstract Epsin 3 (EPN3) expression is limited to gastric parietal cells and wounded or
pathological tissue rather than normal brain tissue, and although it has been identified as an …

Background As the population ages, the proportion of elderly patients with glioblastomas
has increased. Recently, many researchers have focused on the treatments available to and …

Background and purpose To find genetic markers associated with response to radiotherapy
(RT) in glioblastoma (GB) patients. Materials and methods From Jan 2009 to Dec 2016, 161 …

Thyroid cancer patients with radioactive iodine‑refractory or rapidly progressing presentation
require effective treatment. T‑cell originated protein kinase (TOPK) is highly expressed in a …

Methods: A total of 28 patients with GB were studied and categorized into primary and
secondary based on the presence of low-grade areas, ie. discernible astrocytic morphology …