Despite being one of the most frequently carried out chemical reactions in industry, there is
currently no amidation protocol that is regarded as safe, high yielding, environmentally …

The amide functionality is a highly important chemical bond, found in a great number of
synthetic products such as pharmaceuticals, polymers and agrochemicals. The focus of this …

The present review offers an apt summary of amide bond formation with carboxylic acid
substrates by taking advantage of several methods. Carboxamides can be regarded as a …

Triarylsilanols have been reported as the first silicon-centered molecular catalysts for direct
amidation of carboxylic acids with amines as identified after a screen of silanols, silanediols …

Tetramethyl orthosilicate (TMOS) is shown to be an effective reagent for direct amidation of
aliphatic and aromatic carboxylic acids with amines and anilines. The amide products are …

The installation of the C–halogen bond at the ortho position of N-aryl amides and ureas
represents a tool to prepare motifs that are ubiquitous in biologically active compounds. To …

Oxidative stress and hyperlipidemia are important factors for the initiation and progression of
various cell degenerative pathological conditions, including cardiovascular and neurological …

For the first time, we have used activated alumina balls (3–5 mm diameter) for amide
synthesis from carboxylic acids (unactivated) and amines (unactivated) under neat reaction …

It is well-known that amino acids deposited on some inorganic oxides undergo peptidic
condensation. It is seldom realised however that a large diversity of behaviours can be …

An unusual direct amidation of alcohols with nitroarenes mediated by peroxides has been
discovered. The reaction tolerated a wide range of functionalities, and various aromatic …