Myocarditis associated with COVID-19 vaccination

A Buoninfante, A Andeweg, G Genov, M Cavaleri - npj Vaccines, 2024 - nature.com
Following the start of the COVID-19 vaccination campaign, the adverse events of myocarditis
and pericarditis were linked mainly to mRNA COVID-19 vaccines by the regulatory …

[HTML][HTML] Integration of single-cell RNA-seq datasets: a review of computational methods

Y Ryu, GH Han, E Jung, D Hwang - Molecules and cells, 2023 - Elsevier
With the increased number of single-cell RNA sequencing (scRNA-seq) datasets in public
repositories, integrative analysis of multiple scRNA-seq datasets has become …

[HTML][HTML] Development of mRNA vaccines/therapeutics and their delivery system

S Son, K Lee - Molecules and cells, 2023 - Elsevier
The rapid development of mRNA vaccines has contributed to the management of the current
coronavirus disease 2019 (COVID-19) pandemic, suggesting that this technology may be …

Updated considerations for the immunopharmacological aspects of the “talented mRNA vaccines”

C Perrotta, C Fenizia, C Carnovale, M Pozzi… - Vaccines, 2023 - mdpi.com
Messenger RNA (mRNA) vaccines belong to a new class of medications, RNA therapeutics,
including both coding and non-coding RNAs. The use of mRNA as a therapy is based on the …

Single-cell sequencing of PBMC characterizes the altered transcriptomic landscape of classical monocytes in BNT162b2-induced myocarditis

N Hwang, Y Huh, S Bu, KJ Seo, SH Kwon… - Frontiers in …, 2022 - frontiersin.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been the most
dangerous threat to public health worldwide for the last few years, which led to the …

Epigenomic landscape exhibits interferon signaling suppression in the patient of myocarditis after BNT162b2 vaccination

H Kim, HS Ahn, N Hwang, Y Huh, S Bu, KJ Seo… - Scientific Reports, 2023 - nature.com
After the outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
pandemic, a novel mRNA vaccine (BNT162b2) was developed at an unprecedented speed …

Role of immune cells in the pathogenesis of myocarditis

K Liu, B Han - Journal of Leukocyte Biology, 2024 - academic.oup.com
Myocarditis is an inflammatory heart disease that mostly affects young people. Myocarditis
involves a complex immune network; however, its detailed pathogenesis is currently …

Integrated Single‐Cell and RNA Sequencing Analysis Identifies Key Immune Cell and Dendritic Cells Associated Genes Participated in Myocarditis

Q Gong, J Huang, Q Wu - Journal of Immunology Research, 2022 - Wiley Online Library
Myocarditis is a complex disease characterized by myocardial inflammatory cell infiltration.
The purpose of our study was to investigate the gene and single‐cell signature to explore …

Post-COVID-19 Vaccination Myocarditis: A Histopathologic Study on a Monocentric Series of Six Cases

HS Ahn, Y Ahn, J Jang, S Bu, S Lim, C Kim, JM Lee… - Diagnostics, 2024 - mdpi.com
Many reports on the development of myocarditis following coronavirus disease 2019
(COVID-19) vaccination (PCVM) have emerged. However, only a few case studies have …