High drug-loading nanomedicines: progress, current status, and prospects

S Shen, Y Wu, Y Liu, D Wu - International journal of nanomedicine, 2017 - Taylor & Francis
Drug molecules transformed into nanoparticles or endowed with nanostructures with or
without the aid of carrier materials are referred to as “nanomedicines” and can overcome …

Biological properties of Schiff bases and azo derivatives of phenols

P Przybylski, A Huczynski, K Pyta, B Brzezinski… - Current Organic …, 2009 - elibrary.ru
Aza-derivatives of phenols such as Schiff bases and hydrazones are an important and
interesting group of chemical compounds. They exhibit a number of biological activities and …

The antioxidant effect of tannic acid on the in vitro copper-mediated formation of free radicals

RG Andrade Jr, LT Dalvi, JMC Silva Jr… - Archives of Biochemistry …, 2005 - Elsevier
Tannic acid (TA) has well-described antimutagenic and antioxidant activities. The
antioxidant activity of TA has been previously attributed to its capacity to form a complex with …

Reaction chemistry of gossypol and its derivatives

JA Kenar - Journal of the American Oil Chemists' Society, 2006 - Wiley Online Library
Gossypol, a complex polyphenolic compound, is a naturally occurring highly colored yellow
pigment found in the small intercellular pigment glands in the leaves, stems, roots, and seed …

Versatile hyaluronic acid modified AQ4N-Cu (II)-gossypol infinite coordination polymer nanoparticles: multiple tumor targeting, highly efficient synergistic …

S Shen, Y Wu, K Li, Y Wang, J Wu, Y Zeng, D Wu - Biomaterials, 2018 - Elsevier
A novel strategy for the preparation of infinite coordination polymer nanoparticles (ICPs)
based nanomedicines was developed, with which hyaluronic acid modified AQ4N-Cu (II) …

Strand scission in DNA induced by curcumin in the presence of Cu (II)

H Ahsan, SM Hadi - Cancer letters, 1998 - Elsevier
Curcumin, a naturally occurring phytochemical responsible for the colour of turmeric, has
shown a wide range of pharmacological properties including anti-inflammatory, anti-tumour …

Emerging Bcl-2 inhibitors for the treatment of cancer

AS Azmi, Z Wang, PA Philip… - Expert opinion on …, 2011 - Taylor & Francis
Introduction: Bcl-2 family proteins are a component of the antiapoptotic machinery and are
overexpressed in different malignancies. Accordingly, their enhanced expression has been …

Hydroxyl radical is not the main reactive species involved in the degradation of DNA bases by copper in the presence of hydrogen peroxide

S Frelon, T Douki, A Favier, J Cadet - Chemical research in …, 2003 - ACS Publications
Copper is an important biological metal that tightly binds to DNA. Its reaction with
endogenously generated hydrogen peroxide may thus lead to the formation of DNA …

Small molecule inhibitors of bcl-2 family proteins for pancreatic cancer therapy

A Masood, AS Azmi, RM Mohammad - Cancers, 2011 - mdpi.com
Pancreatic cancer (PC) has a complex etiology and displays a wide range of cellular escape
pathways that allow it to resist different treatment modalities. Crucial signaling molecules …

Old wine in a new bottle: the Warburg effect and anticancer mechanisms of resveratrol

I Muqbil, F WJ Beck, B Bao, FH Sarkar… - Current …, 2012 - ingentaconnect.com
Resveratrol found in fruits, vegetables and beverages such as red wine, has been
extensively evaluated for its anticardiovascular disease and cancer preventive effects. Even …