Engineering the next generation of cell-based therapeutics
Cell-based therapeutics are an emerging modality with the potential to treat many currently
intractable diseases through uniquely powerful modes of action. Despite notable recent …
intractable diseases through uniquely powerful modes of action. Despite notable recent …
[HTML][HTML] Solid implantable devices for sustained drug delivery
E Magill, S Demartis, E Gavini, AD Permana… - Advanced Drug Delivery …, 2023 - Elsevier
Implantable drug delivery systems (IDDS) are an attractive alternative to conventional drug
administration routes. Oral and injectable drug administration are the most common routes …
administration routes. Oral and injectable drug administration are the most common routes …
In-vivo programmable acoustic manipulation of genetically engineered bacteria
Acoustic tweezers can control target movement through the momentum interaction between
an acoustic wave and an object. This technology has advantages over optical tweezers for …
an acoustic wave and an object. This technology has advantages over optical tweezers for …
Review of synthetic and hybrid scaffolds in cartilage tissue engineering
M Wasyłeczko, W Sikorska, A Chwojnowski - Membranes, 2020 - mdpi.com
Cartilage tissue is under extensive investigation in tissue engineering and regenerative
medicine studies because of its limited regenerative potential. Currently, many scaffolds are …
medicine studies because of its limited regenerative potential. Currently, many scaffolds are …
[HTML][HTML] Biomaterials to enhance stem cell transplantation
The successful transplantation of stem cells has the potential to transform regenerative
medicine approaches and open promising avenues to repair, replace, and regenerate …
medicine approaches and open promising avenues to repair, replace, and regenerate …
3D printing for preoperative planning and surgical training: a review
Surgeons typically rely on their past training and experiences as well as visual aids from
medical imaging techniques such as magnetic resonance imaging (MRI) or computed …
medical imaging techniques such as magnetic resonance imaging (MRI) or computed …
Inflammation-induced subcutaneous neovascularization for the long-term survival of encapsulated islets without immunosuppression
Cellular therapies for type-1 diabetes can leverage cell encapsulation to dispense with
immunosuppression. However, encapsulated islet cells do not survive long, particularly …
immunosuppression. However, encapsulated islet cells do not survive long, particularly …
[HTML][HTML] Medical devices, smart drug delivery, wearables and technology for the treatment of Diabetes Mellitus
DA Domingo-Lopez, G Lattanzi, LHJ Schreiber… - Advanced drug delivery …, 2022 - Elsevier
Diabetes mellitus refers to a group of metabolic disorders which affect how the body uses
glucose impacting approximately 9% of the population worldwide. This review covers the …
glucose impacting approximately 9% of the population worldwide. This review covers the …
Immune-privileged tissues formed from immunologically cloaked mouse embryonic stem cells survive long term in allogeneic hosts
J Harding, K Vintersten-Nagy, H Yang… - Nature Biomedical …, 2024 - nature.com
The immunogenicity of transplanted allogeneic cells and tissues is a major hurdle to the
advancement of cell therapies. Here we show that the overexpression of eight …
advancement of cell therapies. Here we show that the overexpression of eight …
Hydrogels in emerging technologies for type 1 diabetes
Type 1 diabetes therapies that afford tighter glycemic control in a more manageable and
painless manner for patients has remained a central focus of next-generation diabetes …
painless manner for patients has remained a central focus of next-generation diabetes …