Systemic autoinflammatory diseases (SAIDs) are a group of monogenic diseases
characterized by disordered innate immunity, which causes excessive activation of …

Fever of unknown origin (FUO) can be caused by a wide group of diseases, and can include
both benign and serious conditions. Since the first definition of FUO in the early 1960s …

Background In countries with high child mortality rates, such as Nigeria, early intervention for
common childhood illnesses (eg, pneumonia and malaria) is essential for improving clinical …

NLRP12-related autoinflammatory disease (NLRP12-AID) is an exceptionally rare
autosomal dominant disorder caused by germline mutations in NLRP12 gene. Very few …

Aim Recurrent aphthous stomatitis (RAS) is a painful and common ulcerative form that can
pose a diagnostic challenge. In fact, similar oral ulcers can appear secondary to a variety of …

Background Fever of unknown origin (FUO) has been difficult to diagnose in pediatric
clinical practice. With the gradual change in the disease spectrum, genetic factors have …

Infectious diseases occur very frequently in children and adults. Novel diagnostic methods
have permitted us to expand our knowledge on their epidemiology and pathophysiology [1] …

We present a case of a nine-year-old girl with Crohn's disease whose only first manifestation
was fever. The patient was treated with antibiotics for six weeks by her general practitioner …

Risk Factor Analysis and Risk Prediction Model Construction of Pressure Injury in Critically Ill
Patients with Cancer: A Retrospective Cohort Study in China - PMC Back to Top Skip to main …

Background. NLRP3 gene is located in chromosome 1 and encodes a pyrin‐like protein.
Mutations in this gene are associated with an autoinflammatory disease, called cryopyrin …