Molecular and histopathology directed therapy for advanced bladder cancer

C Alifrangis, U McGovern, A Freeman, T Powles… - Nature Reviews …, 2019 - nature.com
Bladder cancer is a heterogeneous group of tumours with at least 40 histological subgroups.
Patients with localized disease can be cured with surgical resection or radiotherapy, but …

Variants and new entities of bladder cancer

A Lopez‐Beltran, V Henriques, R Montironi… - …, 2019 - Wiley Online Library
Pathological evaluation of bladder cancer typically reveals great tumour heterogeneity, and
therefore the common observation of urothelial carcinoma exhibiting a wide variety of …

Updated results of PURE-01 with preliminary activity of neoadjuvant pembrolizumab in patients with muscle-invasive bladder carcinoma with variant histologies

A Necchi, D Raggi, A Gallina, R Madison, M Colecchia… - European urology, 2020 - Elsevier
Background Patients with predominant variant histology (VH) of bladder tumors, defined as
involving> 50% of the tumor specimens, are typically excluded from clinical trials, and for …

T1 bladder cancer: current considerations for diagnosis and management

B Jordan, JJ Meeks - Nature reviews urology, 2019 - nature.com
Stage T1 bladder cancers invade the lamina propria of the bladder and, despite sharing
many of the genetic features of muscle-invasive bladder cancers, are classified as non …

[HTML][HTML] The prognostic significance of histological subtypes in patients with muscle-invasive bladder cancer: an overview of the current literature

F Claps, A Biasatti, L Di Gianfrancesco… - Journal of Clinical …, 2024 - mdpi.com
Bladder cancer (BC) is the tenth most commonly diagnosed malignancy worldwide. In
approximately 25% of cases, it presents as a muscle-invasive disease, requiring a radical …

[HTML][HTML] Non-muscle-invasive bladder cancer: An overview of potential new treatment options

ND Shore, JP Redorta, G Robert, TE Hutson… - … Oncology: Seminars and …, 2021 - Elsevier
Aim This review article summarizes the current clinical practice guidelines around disease
definitions and risk stratifications, and the treatment of non-muscle-invasive bladder cancer …

Micropapillary urothelial carcinoma of the bladder: a systematic review and meta-analysis of disease characteristics and treatment outcomes

M Abufaraj, B Foerster, E Schernhammer, M Moschini… - European urology, 2019 - Elsevier
Context The optimal treatment of urothelial bladder cancer (UBC) with micropapillary (MP)
variant histology is not clear. Objective To review the current literature on disease …

A systematic review and meta-analysis of variant histology in urothelial carcinoma of the bladder treated with radical cystectomy

K Mori, M Abufaraj, H Mostafaei, F Quhal… - The Journal of …, 2020 - auajournals.org
Purpose: The currently available evidence regarding the prognostic and clinical significance
of each variant histology subtype of urothelial bladder cancer remains scarce. We assessed …

Molecular characterization of neuroendocrine-like bladder cancer

J Batista da Costa, EA Gibb, TJ Bivalacqua, Y Liu… - Clinical cancer …, 2019 - AACR
Purpose: Neuroendocrine (NE) bladder carcinoma is a rare and aggressive variant.
Molecular subtyping studies have found that 5% to 15% of muscle-invasive bladder cancer …

Full-course NIR-II imaging-navigated fractionated photodynamic therapy of bladder tumours with X-ray-activated nanotransducers

L He, L Wang, X Yu, Y Tang, Z Jiang, G Yang… - Nature …, 2024 - nature.com
The poor 5-year survival rate for bladder cancers is associated with the lack of efficient
diagnostic and treatment techniques. Despite cystoscopy-assisted photomedicine and …