BL Sievers, MTK Cheng, K Csiba, B Meng… - Cellular & Molecular …, 2024 - nature.com
An ancient conflict between hosts and pathogens has driven the innate and adaptive arms of immunity. Knowledge about this interplay can not only help us identify biological …
Abstract The SARS-CoV-2 Omicron BA. 1 variant emerged in 2021 and has multiple mutations in its spike protein. Here we show that the spike protein of Omicron has a higher …
FA Lempp, LB Soriaga, M Montiel-Ruiz, F Benigni… - Nature, 2021 - nature.com
Abstract SARS-CoV-2 infection—which involves both cell attachment and membrane fusion— relies on the angiotensin-converting enzyme 2 (ACE2) receptor, which is paradoxically …
COVID-19 is a disease with unique characteristics that include lung thrombosis, frequent diarrhoea, abnormal activation of the inflammatory response and rapid deterioration of lung …
H Fogarty, L Townsend, H Morrin… - … of thrombosis and …, 2021 - Wiley Online Library
Background Persistent symptoms including breathlessness, fatigue, and decreased exercise tolerance have been reported in patients after acute SARS‐CoV‐2 infection. The biological …
B Meng, SA Kemp, G Papa, R Datir, IATM Ferreira… - Cell reports, 2021 - cell.com
We report severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike ΔH69/V70 in multiple independent lineages, often occurring after acquisition of receptor binding motif …
U Gioia, S Tavella, P Martínez-Orellana, G Cicio… - Nature Cell …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the RNA virus responsible for the coronavirus disease 2019 (COVID-19) pandemic. Although SARS-CoV-2 …
MM Rajah, M Hubert, E Bishop, N Saunders… - The EMBO …, 2021 - embopress.org
Severe COVID‐19 is characterized by lung abnormalities, including the presence of syncytial pneumocytes. Syncytia form when SARS‐CoV‐2 spike protein expressed on the …
C Li, J Huang, Y Yu, Z Wan, MC Chiu… - Proceedings of the …, 2023 - National Acad Sciences
The high transmissibility of SARS-CoV-2 Omicron subvariants was generally ascribed to immune escape. It remained unclear whether the emerging variants have gradually …