mRNA-based cancer therapeutics

C Liu, Q Shi, X Huang, S Koo, N Kong, W Tao - Nature Reviews Cancer, 2023 - nature.com
Due to the fact that mRNA technology allows the production of diverse vaccines and
treatments in a shorter time frame and with reduced expense compared to conventional …

Emerging mRNA technologies: delivery strategies and biomedical applications

Y Xiao, Z Tang, X Huang, W Chen, J Zhou… - Chemical Society …, 2022 - pubs.rsc.org
The great success achieved by the two highly-effective messenger RNA (mRNA) vaccines
during the COVID-19 pandemic highlights the great potential of mRNA technology. Through …

[HTML][HTML] Engineering nanoparticle toolkits for mRNA delivery

B Sun, W Wu, EA Narasipura, Y Ma, C Yu… - Advanced Drug Delivery …, 2023 - Elsevier
The concept of using mRNA to produce its own medicine in situ in the body makes it an ideal
drug candidate, holding great potential to revolutionize the way we approach medicine. The …

[HTML][HTML] Hyaluronic acid-based nanoplatforms for Doxorubicin: A review of stimuli-responsive carriers, co-delivery and resistance suppression

M Ashrafizadeh, S Mirzaei, MH Gholami… - Carbohydrate …, 2021 - Elsevier
An important motivation for the use of nanomaterials and nanoarchitectures in cancer
therapy emanates from the widespread emergence of drug resistance. Although doxorubicin …

Tools for translation: non-viral materials for therapeutic mRNA delivery

KA Hajj, KA Whitehead - Nature Reviews Materials, 2017 - nature.com
In recent years, messenger RNA (mRNA) has come into the spotlight as a versatile
therapeutic with the potential to prevent and treat a staggering range of diseases. Billions of …

Functional graphene nanomaterials based architectures: biointeractions, fabrications, and emerging biological applications

C Cheng, S Li, A Thomas, NA Kotov, R Haag - Chemical reviews, 2017 - ACS Publications
Functional graphene nanomaterials (FGNs) are fast emerging materials with extremely
unique physical and chemical properties and physiological ability to interfere and/or interact …

Graphene-based nanomaterials for drug and/or gene delivery, bioimaging, and tissue engineering

H Zhao, R Ding, X Zhao, Y Li, L Qu, H Pei… - Drug Discovery …, 2017 - Elsevier
Highlights•Graphene-based nanomaterials are emerging as the next generation's
candidates for biotechnological advancements.•Graphene and its various derivatives have …

Biomedical applications of carbon nanomaterials: Drug and gene delivery potentials

M Mohajeri, B Behnam… - Journal of cellular …, 2019 - Wiley Online Library
One of the major components in the development of nanomedicines is the choice of the right
biomaterial, which notably determines the subsequent biological responses. The popularity …

The nano delivery systems and applications of mRNA

M Li, Y Li, S Li, L Jia, H Wang, M Li, J Deng… - European journal of …, 2022 - Elsevier
The current COVID-19 epidemic has greatly accelerated the application of mRNA
technology to our real world, and during this battle mRNA has proven it's unique advantages …

Advances in mRNA therapeutics for cancer immunotherapy: from modification to delivery

G Han, D Noh, H Lee, S Lee, S Kim, HY Yoon… - Advanced Drug Delivery …, 2023 - Elsevier
RNA vaccines have demonstrated their ability to solve the issues posed by the COVID-19
pandemic. This success has led to the renaissance of research into mRNA and their …