Tourette's syndrome

J Jankovic - New England Journal of Medicine, 2001 - Mass Medical Soc
The French neurologist Georges Gilles de la Tourette first described this syndrome, which
consists of motor tics sometimes accompanied by uncontrollable noises or utterances …

Closed-loop neurostimulation for the treatment of psychiatric disorders

KK Sellers, JL Cohen, AN Khambhati, JM Fan… - …, 2024 - nature.com
Despite increasing prevalence and huge personal and societal burden, psychiatric diseases
still lack treatments which can control symptoms for a large fraction of patients. Increasing …

Closed-loop stimulation in periods with less epileptiform activity drives improved epilepsy outcomes

DN Anderson, CM Charlebois, EH Smith, TS Davis… - Brain, 2024 - academic.oup.com
In patients with drug-resistant epilepsy, electrical stimulation of the brain in response to
epileptiform activity can make seizures less frequent and debilitating. This therapy, known as …

An update on the pharmacological management of Tourette syndrome and emerging treatment paradigms

A Lenka, J Jankovic - Expert Review of Neurotherapeutics, 2024 - Taylor & Francis
Introduction Tourette syndrome (TS) is a childhood-onset neurobehavioral disorder
characterized by tics. Pharmacotherapy is advised for patients whose symptoms affect their …

[HTML][HTML] Perspectives of implementation of closed-loop deep brain stimulation: from neurological to psychiatric disorders

S Groppa, G Gonzalez-Escamilla… - Stereotactic and …, 2024 - karger.com
Background: Deep brain stimulation (DBS) is a highly efficient, evidence-based therapy to
alleviate symptoms and improve quality of life in movement disorders such as Parkinson's …

Proceedings of the 10th annual deep brain stimulation think tank: Advances in cutting edge technologies, artificial intelligence, neuromodulation, neuroethics …

JK Wong, HS Mayberg, DD Wang… - Frontiers in Human …, 2023 - frontiersin.org
The deep brain stimulation (DBS) Think Tank X was held on August 17–19, 2022 in Orlando
FL. The session organizers and moderators were all women with the theme women in …

Responsive deep brain stimulation for the treatment of Tourette syndrome

MS Okun, J Cagle, J Gomez, D Bowers, J Wong… - Scientific Reports, 2024 - nature.com
To report the results of 'responsive'deep brain stimulation (DBS) for Tourette syndrome (TS)
in a National Institutes of Health funded experimental cohort. The use of 'brain derived …

Challenges and opportunities of acquiring cortical recordings for chronic adaptive deep brain stimulation

J Herron, A Kullmann, T Denison… - Nature Biomedical …, 2024 - nature.com
Deep brain stimulation (DBS), a proven treatment for movement disorders, also holds
promise for the treatment of psychiatric and cognitive conditions. However, for DBS to be …

Proceedings of the 11th Annual Deep Brain Stimulation Think Tank: pushing the forefront of neuromodulation with functional network mapping, biomarkers for …

KA Johnson, NUF Dosenbach, EM Gordon… - Frontiers in Human …, 2024 - frontiersin.org
The Deep Brain Stimulation (DBS) Think Tank XI was held on August 9–11, 2023 in
Gainesville, Florida with the theme of “Pushing the Forefront of Neuromodulation”. The …

Alternative patterns of deep brain stimulation in neurologic and neuropsychiatric disorders

RA Najera, AK Mahavadi, AU Khan… - Frontiers in …, 2023 - frontiersin.org
Deep brain stimulation (DBS) is a widely used clinical therapy that modulates neuronal firing
in subcortical structures, eliciting downstream network effects. Its effectiveness is determined …