Covering: 1990 to 2015 The clerodane diterpenoids are a widespread class of secondary
metabolites and have been found in several hundreds of plant species from various families …

Liver disease is any condition that may cause liver inflammation or tissue damage and
affects liver function. Natural products that are found in vegetables, fruits, plant extracts …

Objective Bay leaf, one of the plants in Indonesia that has been shown to have activities to
reduce cholesterol in the blood. HMG-CoA Reductase inhibition is one of many mechanisms …

A new concise construction of trans-clerodane diterpenoids is reported in which oxacyclic
and trans-hydronaphthalene fragments are coupled, and the critical C9-quaternary carbon …

Phytochemical studies of methylene chloride soluble fraction from the 70% aqueous-
alcoholic extract of Polyalthia longifolia (leaves) resulted in the isolation of two known …

This study was performed to investigate the mechanistic aspects of cell death induced by a
clerodane diterpene (K-09) in Leishmania donovani promastigotes that was previously …

In the pursuance of novel scaffolds with promising antiplasmodial and anti-inflammatory
activity, a series of twenty-one compounds embraced with most promising penta-substituted …

Background The current perspective for the search of 3-hydroxy-3-methyl-glutaryl-coenzyme
A (HMG-CoA) reductase inhibitor has been shifted towards a natural agent also having …

Polyalthia belong to the Annonaceae family and are a type of evergreen tree distributed
across many tropical and subtropical regions. Polyalthia species have been used long term …

Cardiovascular diseases (CVDs) are a leading cause of global morbidity, mortality, and
health care spending. The current goal of the United Nations is a 25% reduction in deaths …