The central proteins for protection against tuberculosis are attributed to interferon-γ, tumor
necrosis factor-α, interleukin (IL)-6 and IL-1β, while IL-10 primarily suppresses anti …

The role of the endocrine system on the immune response, especially in the lung, remains
poorly understood. Hormones play a crucial role in the development, homeostasis …

Different lines of evidence demonstrate that microRNAs (miRNAs) play an important role in
host–pathogen interactions. In this study we investigated the expression patterns of several …

Background Tuberculosis (TB) is a serious infectious disease in that 90% of those latently
infected with Mycobacterium tuberculosis present no symptoms, but possess a 10% lifetime …

Background Cachexia is a hallmark of pulmonary tuberculosis and is associated with poor
prognosis. A better understanding of the mechanisms behind such weight loss could reveal …

Mycobacterium tuberculosis (Mtb) causes nearly 10 millions of new tuberculosis disease
cases annually. However, most individuals exposed to Mtb do not develop tuberculosis …

Background Female genital tuberculosis (FGTB), an important clinical sub‐type of extra‐
pulmonary tuberculosis (EPTB) is responsible for about 10% cases of infertility in India. Both …

Upon the pathogen encounter, the host seeks to ensure an adequate inflammatory reaction
to combat infection but at the same time tries to prevent collateral damage, through several …

Background Wasting is known as a prominent feature of tuberculosis (TB). To monitor the
disease state, markers of metabolism and inflammation are potentially useful. We thus …

Several studies have documented the interaction between the immune and endocrine
systems as an effective defense strategy against tuberculosis, involving the production of …