[HTML][HTML] Organ-on-a-chip microengineering for bio-mimicking disease models and revolutionizing drug discovery
T Ahmed - Biosensors and Bioelectronics: X, 2022 - Elsevier
The core of the drug research and screening processes is predicting the effect of drugs prior
to human clinical trials. Due to the 2D cell culture and animal models' poor predictability, the …
to human clinical trials. Due to the 2D cell culture and animal models' poor predictability, the …
Organ-on-a-Chip systems for new drugs development
R Vargas, A Egurbide-Sifre, L Medina - ADMET and DMPK, 2021 - hrcak.srce.hr
Sažetak Research on alternatives to the use of animal models and cell cultures has led to
the creation of organ-on-a-chip systems, in which organs and their physiological reactions to …
the creation of organ-on-a-chip systems, in which organs and their physiological reactions to …
In silico prediction of chemical-induced hematotoxicity with machine learning and deep learning methods
Y Hua, Y Shi, X Cui, X Li - Molecular Diversity, 2021 - Springer
Chemical-induced hematotoxicity is an important concern in the drug discovery, since it can
often be fatal when it happens. It is quite useful for us to give special attention to chemicals …
often be fatal when it happens. It is quite useful for us to give special attention to chemicals …
Rapid Biofabrication of an Advanced Microphysiological System Mimicking Phenotypical Heterogeneity and Drug Resistance in Glioblastoma
S Pun, A Prakash, D Demaree… - Advanced …, 2024 - Wiley Online Library
Microphysiological systems (MPSs) reconstitute tissue interfaces and organ functions,
presenting a promising alternative to animal models in drug development. However …
presenting a promising alternative to animal models in drug development. However …
[引用][C] Organ-on-a-Chip systems for new drugs development
R Vargas Monge, L Medina, A Egurbide Sifre - 2021