Abstract β-Lactam antibiotics are one of the most relevant drug classes of antibacterial
agents worldwide. The discovery and the market of first β-lactam antibiotic (Penicillin G) is a …

Zinc (Zn) is one of the most important essential nutrients of great public health significance. It
is involved in numerous biological functions and it is considered as a multipurpose trace …

Abstract Development of antibiotic resistance in bacteria is one of the major issues in the
present world and one of the greatest threats faced by mankind. Resistance is spread …

Carbapenem‐resistant Enterobacteriaceae (CRE) have been listed by the WHO as high‐
priority pathogens owing to their high association with mortalities and morbidities …

Carbapenem resistance is a major global health problem that seriously compromises the
treatment of infections caused by nosocomial pathogens. Resistance to carbapenems …

Antibiotic resistance caused by β-lactamase production continues to present a growing
challenge to the efficacy of β-lactams and their role as the most important class of clinically …

Microbial pathogens including Enterobacteriaceae family members bear different antibiotic
resistance genes comprising Extended-Spectrum-ß-Lactamases (ESBLs) and Metallo-ß …

Antimicrobial susceptibility testing (AST) of cefiderocol poses challenges because of its
unique mechanism of action (ie, requiring an iron-depleted state) and due to differences in …

The spread of carbapenem-and polymyxin-resistant Enterobacteriaceae poses a significant
threat to public health, challenging clinicians worldwide with limited therapeutic options. This …

The rise of antibiotic resistance calls for new therapeutics targeting resistance factors such
as the New Delhi metallo-β-lactamase 1 (NDM-1), a bacterial enzyme that degrades β …