Clinical detection, diagnosis and treatment of morphological abnormalities of sperm flagella: A review of literature

J Wang, W Wang, L Shen, A Zheng, Q Meng, H Li… - Frontiers in …, 2022 - frontiersin.org
Sperm carries male genetic information, and flagella help move the sperm to reach oocytes.
When the ultrastructure of the flagella is abnormal, the sperm is unable to reach the oocyte …

Ubiquitin‐specific peptidases: Players in bone metabolism

J Shen, X Lin, F Dai, G Chen, H Lin, B Fang… - Cell …, 2023 - Wiley Online Library
Osteoporosis is an ageing‐related disease, that has become a major public health problem
and its pathogenesis has not yet been fully elucidated. Substantial evidence suggests a …

Bi-allelic variants in DNHD1 cause flagellar axoneme defects and asthenoteratozoospermia in humans and mice

C Tan, L Meng, M Lv, X He, Y Sha, D Tang… - The American Journal of …, 2022 - cell.com
Asthenoteratozoospermia, defined as reduced sperm motility and abnormal sperm
morphology, is a disorder with considerable genetic heterogeneity. Although previous …

Successful results of intracytoplasmic sperm injection of a Chinese patient with multiple morphological abnormalities of sperm flagella caused by a novel splicing …

J Wang, C Zhang, H Tang, A Zheng, H Li, S Yang… - Frontiers in …, 2022 - frontiersin.org
Asthenospermia is one of the most important causes of male infertility. Among
asthenospermia, multiple morphological abnormalities of sperm flagella (MMAF) are …

CCDC146 is required for sperm flagellum biogenesis and male fertility in mice

Y Ma, B Wu, Y Chen, S Ma, L Wang, T Han… - Cellular and Molecular …, 2024 - Springer
Multiple morphological abnormalities of the flagella (MMAF) is a severe disease of male
infertility, while the pathogenetic mechanisms of MMAF are still incompletely understood …

Deleterious variants in X-linked RHOXF1 cause male infertility with oligo- and azoospermia

S Yi, W Wang, L Su, L Meng, Y Li, C Tan… - Molecular Human …, 2024 - academic.oup.com
Oligozoospermia and azoospermia are two common phenotypes of male infertility
characterized by massive sperm defects owing to failure of spermatogenesis. The …

[HTML][HTML] Genetic Risk Loci and Familial Associations in Migraine: A Genome-Wide Association Study in the Han Chinese Population of Taiwan

Y Liu, PK Yeh, YK Lin, CS Liang, CL Tsai… - Journal of Clinical …, 2023 - thejcn.com
Background and Purpose Migraine is a condition that is often observed to run in families, but
its complex genetic background remains unclear. This study aimed to identify the genetic …