Background Worldwide rising trend in infertility has been observed in the past few years with
male infertility arising as a major problem. One main reason for the rise in male infertility …

Background Male infertility is a widespread condition among couples. In about 50% of
cases, couple infertility is attributable to the male partner, mainly due to a failure in …

Oocytes form before birth and remain viable for several decades before fertilization.
Although poor oocyte quality accounts for most female fertility problems, little is known about …

Contemporary analyses of cell metabolism have called out three metabolites: ATP, NADH,
and acetyl-CoA, as sentinel molecules whose accumulation represent much of the purpose …

Carbohydrate metabolism is essential for cellular energy balance as well as for the
biosynthesis of new cellular building blocks. As animal nutrient intake displays temporal …

Mitochondria are central hubs for energy production, metabolism and cellular signal
transduction in eukaryotic cells. Maintenance of mitochondrial homeostasis is important for …

Photosynthesis is the major process leading to primary production in the Biosphere. There is
a total of 7000bn tons of CO2 in the atmosphere and photosynthesis fixes more than 100bn …

Insulin signaling regulates various aspects of physiology, such as glucose homeostasis and
aging, and is a key determinant of female reproduction in metazoans. That insulin signaling …

Pluripotent cells from the early stages of embryonic development have the unlimited
capacity to self-renew and undergo differentiation into all of the cell types of the adult …

Pancreatic ductal adenocarcinoma (PDAC) cells have a great demand for nutrients in the
form of sugars, amino acids, and lipids. Particularly, amino acids are critical for cancer …