Lost in traffic: consequences of altered palmitoylation in neurodegeneration

F Ramzan, F Abrar, GG Mishra, LMQ Liao… - Frontiers in …, 2023 - frontiersin.org
One of the first molecular events in neurodegenerative diseases, regardless of etiology, is
protein mislocalization. Protein mislocalization in neurons is often linked to proteostasis …

Gain of function screen of PATs reveals an essential role of Hip14 in Drosophila host defense

Z Deng, H Chen, L Xiao, H Jin… - Journal of genetics …, 2023 - pubmed.ncbi.nlm.nih.gov
Gain of function screen of PATs reveals an essential role of Hip14 in Drosophila host defense
Gain of function screen of PATs reveals an essential role of Hip14 in Drosophila host defense …

Assessing functional impact of amino acid alterations in proteins

JC Gonzalez Sanchez - 2022 - archiv.ub.uni-heidelberg.de
Genome sequencing efforts, coupled with technological advances and cost reductions, have
led to the discovery of an increasing number of disease-related genetic variants. For the vast …