Ubiquitylomics: An Emerging Approach for Profiling Protein Ubiquitylation in Skeletal Muscle

SO Lord, HE Johnston, RS Samant… - Journal of cachexia …, 2024 - Wiley Online Library
Skeletal muscle is a highly adaptable tissue, finely tuned by various physiological and
pathological factors. Whilst the pivotal role of skeletal muscle in overall health is widely …

Characteristics of transcriptome and metabolome concerning intramuscular fat content in Beijing Black Pigs

X Hou, R Zhang, M Yang, N Niu, W Zong… - Journal of Agricultural …, 2023 - ACS Publications
To study the characteristics of genes and metabolites related to intramuscular fat (IMF)
content with less influence by breed background and individual differences, the skeletal …

Tamoxifen improves muscle structure and function of Bin1- and Dnm2-related centronuclear myopathies

C Gineste, A Simon, M Braun, D Reiss, J Laporte - Brain, 2023 - academic.oup.com
Congenital myopathies define a genetically heterogeneous group of disorders associated
with severe muscle weakness, for which no therapies are currently available. Here we …

The main sources of molecular organization in the cell. Atlas of self-organized and self-regulated dynamic biostructures

M Ildefonso, JM Cortes, I Malaina… - Progress in Biophysics …, 2025 - Elsevier
One of the most important goals of contemporary biology is to understand the principles of
the molecular order underlying the complex dynamic architecture of cells. Here, we present …

Expression patterns of housekeeping genes and tissue-specific genes in black goats across multiple tissues

C Qin, D Wang, H Han, Y Cao, X Wang, Z Xuan… - Scientific Reports, 2024 - nature.com
Black goats are a significant meat breed in southern China. To investigate the expression
patterns and biological functions of genes in various tissues of black goats, we analyzed …

Beta2‐Adrenergic Stimulation Induces Resistance Training‐Like Adaptations in Human Skeletal Muscle: Potential Role of KLHL41

S Jessen, JP Quesada, A Di Credico… - … Journal of Medicine …, 2024 - Wiley Online Library
Skeletal muscle mass plays a pivotal role in metabolic function, but conditions such as bed
rest or injury often render resistance training impractical. The beta2‐adrenergic receptor has …

Standardization of zebrafish drug testing parameters for muscle diseases

M Karuppasamy, KG English… - Disease Models & …, 2024 - journals.biologists.com
Skeletal muscular diseases predominantly affect skeletal and cardiac muscle, resulting in
muscle weakness, impaired respiratory function and decreased lifespan. These harmful …

Zebrafish as an Emerging Model for Sarcopenia: Considerations, Current Insights, and Future Directions

S Callegari, F Mirzaei, L Agbaria, S Shariff… - International Journal of …, 2023 - mdpi.com
Sarcopenia poses a significant challenge to public health and can severely impact the
quality of life of aging populations. Despite extensive efforts to study muscle degeneration …

[HTML][HTML] SAR1A Induces Cell Growth and Epithelial–Mesenchymal Transition Through the PI3K/AKT/mTOR Pathway in Head and Neck Squamous Cell Carcinoma: An …

S Fang, J Wang, T Liu, Y Jiang, Q Hua - Biomedicines, 2024 - mdpi.com
Objectives: Head and neck squamous cell carcinoma (HNSCC) ranks sixth globally, with a
50% five-year survival rate. SAR1A exhibits high expression levels in various tumor types …

[HTML][HTML] Uncovering the profile of ubiquitination motif in catalytic proteins using sequence contextual features

Y Zhang, Y Ai, Q Fan, B Chen, J Zhang, Y Lv… - Animals and …, 2024 - Elsevier
Ubiquitin molecules modify their target protein by conjugating the amino group of lysine side
chain, thereby regulating the activity and function of most intracellular proteins. However …