New developments in the pathogenesis, therapeutic targeting, and treatment of pediatric medulloblastoma

FY Fang, JS Rosenblum, WS Ho, JD Heiss - Cancers, 2022 - mdpi.com
Simple Summary Medulloblastoma is the most common pediatric brain tumor, comprising
one-third of all pediatric brain tumors, and originating in the posterior fossa of the brain. The …

Molecular stratifications, biomarker candidates and new therapeutic options in current medulloblastoma treatment approaches

O Menyhárt, B Győrffy - Cancer and Metastasis Reviews, 2020 - Springer
Medulloblastoma (MB) is the most common malignant childhood tumor of the brain.
Multimodal treatment consisting of surgery, radiation therapy, and chemotherapy reduced …

Medulloblastoma: optimizing care with a multidisciplinary approach

A Thomas, G Noël - Journal of multidisciplinary healthcare, 2019 - Taylor & Francis
Medulloblastoma is a malignant tumor of the cerebellum and the most frequent malignant
brain tumor in children. The standard of care consists of maximal resection surgery, followed …

Risk factors for survival in patients with medulloblastoma: a systematic review and meta-analysis

Y Liu, B Xiao, S Li, J Liu - Frontiers in Oncology, 2022 - frontiersin.org
Background Conventional parameters show limited and unreliable correlations with
medulloblastoma prognosis. Aim To evaluate the factors influencing overall survival (OS) …

[HTML][HTML] Evaluation of Prognostic Factors and Role of Participation in a Randomized Trial or a Prospective Registry in Pediatric and Adolescent Nonmetastatic …

S Dietzsch, F Placzek, K Pietschmann… - Advances in Radiation …, 2020 - Elsevier
Purpose We aimed to compare treatment results in and outside of a randomized trial and to
confirm factors influencing outcome in a large retrospective cohort of nonmetastatic …

Medulloblastoma: an old diagnosis with new promises

L Szalontay, Y Khakoo - Current oncology reports, 2020 - Springer
Abstract Purpose of Review Molecular subtyping in medulloblastoma (MB) has diagnostic
and prognostic values which impact therapy. This paper provides guidance for the clinician …

Treatment of hydrocephalus following posterior fossa tumor resection: a multicenter collaboration from the hydrocephalus clinical research network

MC Dewan, AM Isaacs, MJ Cools… - Journal of neuro …, 2023 - Springer
Objective Persistent hydrocephalus following posterior fossa brain tumor (PFBT) resection is
a common cause of morbidity in pediatric brain tumor patients, for which the optimal …

Racial and ethnic disparities in brain tumour survival by age group and tumour type

A Delavar, AR Wali, DR Santiago-Dieppa… - British Journal of …, 2022 - Taylor & Francis
Purpose The extent to which racial/ethnic brain tumour survival disparities vary by age is not
very clear. In this study, we assess racial/ethnic brain tumour survival disparities overall by …

Postoperative hydrocephalus management may cause delays in adjuvant treatment following paediatric posterior fossa tumour resection: a multicentre retrospective …

I Ben Zvi, G Adegboyega, SM Toescu, N Schwartz… - Child's Nervous …, 2022 - Springer
Abstract Introduction Hydrocephalus persists in 10–40% of children with posterior fossa
tumours (PFT). A delay in commencement of adjuvant therapy (AT) can negatively influence …

Referral patterns and treatment delays in medulloblastoma: a large academic proton center experience

SM Liu, ED Brooks, ML Rubin… - … Journal of Particle …, 2021 - meridian.allenpress.com
Purpose Patient travel time can cause treatment delays when providers and families decide
to seek proton therapy. We examined whether travel distance or referral pattern (domestic …