A survey of protein databases indicates that the majority of enzymes exist in oligomeric
forms, with about half of those found in the UniProt database being homodimeric …

Biology spans a continuum of length and time scales. Individual experimental methods only
glimpse discrete pieces of this spectrum but can be combined to construct a more holistic …

The ultimate microscope, directed at a cell, would reveal the dynamics of all the cell's
components with atomic resolution. In contrast to their real-world counterparts …

Despite the vast diversity of the antibody repertoire, infected individuals often mount
antibody responses to precisely the same epitopes within antigens. The immunological …

Influenza virus has resurfaced recently from inactivity during the early stages of the COVID-
19 pandemic, raising serious concerns about the nature and magnitude of future epidemics …

Predicting electronic energies, densities, and related chemical properties can facilitate the
discovery of novel catalysts, medicines, and battery materials. However, existing machine …

Molecular dynamics (MD) simulations are keeping computers busy around the world,
generating a huge amount of data that is typically not open to the scientific community …

The catalytic activity of human glutathione S‐transferase A1‐1 (hGSTA1‐1), a homodimeric
detoxification enzyme, is dependent on the conformational dynamics of a key C‐terminal …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein is the
prime target for vaccines, diagnostics, and therapeutic antibodies against the virus. While …

Complex carbohydrates (glycans) are the most abundant and versatile biopolymers in
nature. The broad diversity of biochemical functions that carbohydrates cover is a direct …