The tumor cell signaling pathways that trigger the uncontrolled proliferation, resistance to
apoptosis, metastasis and escape from immune surveillance are partially understood. Toll …

Toll-like receptors (TLRs) belong to a class of pattern-recognition receptors that play an
important role in host defense against pathogens by recognizing a wide variety of pathogen …

Toll-like receptors (TLRs) play a crucial role in the innate immune response and the
subsequent induction of adaptive immune responses against microbial infection or tissue …

Infectious complications resulting from resection of colorectal cancer (CRC) elevates the risk
of cancer recurrence and metastasis, but the reason for this risk relationship is unknown …

The aim of the present study was to evaluate the expression of innate immunity receptors
belonging to the Toll-like family in the neural plexuses of the different tracts of murine …

Damage-associated molecular patterns (DAMPs) are danger signals (or alarmins) alerting
immune cells through pattern recognition receptors (PRRs) to begin defense activity …

Cancer immunotherapy has been the focus of intense research since the late 19th century
when Coley observed that bacterial components can contribute to cancer regression by …

Background Tumor cell expression of Toll-like receptors (TLRs) can promote inflammation
and cell survival in the tumor microenvironment. Toll-like receptor 4 (TLR4) signaling in …

Abstract Toll-like receptors (TLRs), mainly expressing in human immune related cells and
epithelial cells, play an essential role in the host defense against microbes by recognizing …

Toll-like receptors (TLRs) play essential roles in generating innate immune responses, and
are evolutionarily conserved across species. In mammals, TLRs specifically recognize the …