Therapeutic significance of β-glucuronidase activity and its inhibitors: A review

P Awolade, N Cele, N Kerru, L Gummidi… - European journal of …, 2020 - Elsevier
The emergence of disease and dearth of effective pharmacological agents on most
therapeutic fronts, constitutes a major threat to global public health and man's existence …

Fungal gut microbiota dysbiosis and its role in colorectal, oral, and pancreatic carcinogenesis

K Kaźmierczak-Siedlecka, A Dvořák, M Folwarski… - Cancers, 2020 - mdpi.com
The association between bacterial as well as viral gut microbiota imbalance and
carcinogenesis has been intensively analysed in many studies; nevertheless, the role of …

Highly fluorescent N-doped carbon dots with two-photon emission for ultrasensitive detection of tumor marker and visual monitor anticancer drug loading and delivery

P Gong, L Sun, F Wang, X Liu, Z Yan, M Wang… - Chemical Engineering …, 2019 - Elsevier
Early diagnosis and therapy are practically important to effectively prevent cancer and
improve patients' life quality. Herein, a simple and sensitive two-photon imaging fluorescent …

Nutritional value and biological activity of gluten-free bread enriched with cricket powder

PŁ Kowalczewski, M Gumienna, I Rybicka, B Górna… - Molecules, 2021 - mdpi.com
Cricket powder, described in the literature as a source of nutrients, can be a valuable
ingredient to supplement deficiencies in various food products. Work continues on the …

Intestinal bacterial β-glucuronidase as a possible predictive biomarker of irinotecan-induced diarrhea severity

AN Chamseddine, M Ducreux, JP Armand… - Pharmacology & …, 2019 - Elsevier
Irinotecan is an anticancer drug with a broad spectrum of activity, characterized by multistep
and complex pharmacology. Regardless of its schedule of administration, neutropenia and …

Facile and ultrasensitive fluorescence sensor platform for tumor invasive biomaker β-glucuronidase detection and inhibitor evaluation with carbon quantum dots …

S Lu, G Li, Z Lv, N Qiu, W Kong, P Gong, G Chen… - Biosensors and …, 2016 - Elsevier
Early detection and diagnosis have great practical significances for the effective prevention
and treatment of cancer. In this study, we developed a novel, facile and ultra-sensitive …

Relationship between gut microbiota and colorectal cancer: Probiotics as a potential strategy for prevention

SY Lee, JH Kang, JH Kim, JW Jeong, HW Kim… - Food Research …, 2022 - Elsevier
Gut microbiota comprise microorganisms residing in the gastrointestinal tract. Some of these
microbiota are implicated in the progression of colorectal cancer (CRC). Here, we highlight …

Turn-on fluorescence detection of β-glucuronidase using RhB@ MOF-5 as an ultrasensitive nanoprobe

L Guo, Y Liu, R Kong, G Chen, H Wang, X Wang… - Sensors and Actuators B …, 2019 - Elsevier
Abstract β-Glucuronidase (β-GCU) is closely related to the occurrence of multiple diseases,
and it has been applied as a biomarker and therapeutic target in clinical diagnosis …

Understanding the role of gut microfloral bifidobacterium in cancer and its potential therapeutic applications

D Sharma, D Gajjar, S Seshadri - Microbiome Research …, 2023 - pmc.ncbi.nlm.nih.gov
Gut microbiota research has gained a tremendous amount of attention from the scientific
community because of its contribution to gut homeostasis, human health, and various …

Ratiometric fluorescence and chromaticity dual-readout assay for β-glucuronidase activity based on luminescent lanthanide metal-organic framework

S Li, L Yu, L Xiong, Y Xiao - Sensors and Actuators B: Chemical, 2022 - Elsevier
Abstract β-Glucuronidase (GCU) is a biomarker of many malignant tumors. The accurate and
sensitive detection of GCU is of significance for the early diagnosis of diseases. Herein, we …