Obesity has been well recognized as an important comorbidity in patients with asthma,
representing a unique phenotype and endotype. This association indicates a close …

Obesity is a chronic illness associated with several metabolic derangements and
comorbidities (ie, insulin resistance, leptin resistance, diabetes, etc.) and often leads to …

Epidemiological studies have shown a dramatic increase in the incidence and the
prevalence of allergic diseases over the last several decades. Environmental triggers …

Although eosinophilic inflammation is characteristic of asthma pathogenesis, neutrophilic
inflammation is also marked, and eosinophils and neutrophils can coexist in some cases …

Abstract Rationale and Objective Plasma extracellular vesicles (EVs) represent a vital
source of molecular information about health and disease states. Due to their heterogenous …

Although non-eosinophilic asthma (NEA) is not the best known and most prevalent asthma
phenotype, its importance cannot be underestimated. NEA is characterized by airway …

The term (bronchial) asthma describes a disorder syndrome that comprises several disease
phenotypes, all characterized by chronic inflammation in the bronchial epithelium, with a …

Over the past decades, the relationship between the immune system and metabolism has
become a major research focus. In this arena of immunometabolism the capacity of adipose …

Extracellular vesicles (EVs) are membranous structures, which are secreted by almost every
cell type analyzed so far. In addition to their importance for cell-cell communication under …

Asthma is a chronic inflammatory disease of the respiratory tract characterized by recurrent
breathing problems resulting from airway obstruction and hyperresponsiveness. Human …