Effect of pharmaceutical excipients on micellization of Pluronic and the application as drug carrier to reverse MDR

Y Li, Y Tian, X Jia, Z Zhang, D Sun, H Xie… - Journal of Molecular …, 2023 - Elsevier
Linear amphiphilic triblock copolymers Pluronic, poly (ethylene oxide)-poly (propylene
oxide)-poly (ethylene oxide)(PEO-PPO-PEO) have been widely used in controllable drug …

Salt induced micellization conduct in PEO–PPO–PEO-based block copolymers: a thermo-responsive approach

N Tripathi, D Ray, VK Aswal, K Kuperkar, P Bahadur - Soft Matter, 2023 - pubs.rsc.org
The nanoscale self-assembly behavior in ethylene oxide (EO) and propylene oxide (PO)-
based block copolymers (BCPs) commercially available as Pluronics®: L44 (PEO10–PPO23 …

Advancements in micellar formulation: drug delivery vehicle for water-insoluble drugs

L Sharma, D Khurana, P Patel, S Khare… - Recent Advances in …, 2024 - benthamdirect.com
Micellar systems, particularly polymeric micelles, have emerged as a promising drug
delivery vehicle for water-insoluble compounds. Polymeric micelles, self-assembled …

Nanoscale Pluronic® micellar templates with varying% EO content for controlled drug release and cytotoxicity

N Tripathi, G Singhvi, A Roy, K Kuperkar… - Journal of Molecular …, 2023 - Elsevier
This study investigates the self-assembly in ethylene oxide (EO)-propylene oxide (PO)-
based block copolymers (BCPs) with various molecular features like molecular weight …

Rationalizing the design of Pluronics–surfactant mixed micelles through molecular simulations and experiments

D Patel, G Perez-Sanchez, M Jorge, D Ray, VK Aswal… - Langmuir, 2023 - ACS Publications
Aqueous systems comprising polymers and surfactants are technologically important
complex fluids with tunable features dependent on the chemical nature of each constituent …

Glucose-induced self-assembly and phase separation in hydrophilic triblock copolymers and the governing mechanism

D Patel, AK Bhojani, D Ray, DK Singh… - Physical Chemistry …, 2022 - pubs.rsc.org
Poly (ethylene oxide, EO)–poly (propylene oxide, PO)–poly (ethylene oxide, EO)-based
triblock copolymers (BCPs) with 80% hydrophilicity stay molecularly dissolved as Gaussian …

Co-micellization conduct and structural dynamics of block copolymers in water and salt solution environment for drug solubilization enhancement

D Patel, SL Gawali, K Kuperkar, PA Hassan… - Colloid and Polymer …, 2023 - Springer
The present study examines the co-micellization in different block copolymers (BCPs): P123
and F127 (with almost similar hydrophobic PO block but different hydrophilic% EO content) …

Role of Unimers to Polymersomes Transition in Pluronic Blends for Controlled and Designated Drug Conveyance

D Patel, N Tripathi, P Vaswani… - The Journal of …, 2024 - ACS Publications
This study investigates the nanoscale self-assembly from mixtures of two symmetrical poly
(ethylene oxide)-poly (propylene oxide)-pol (ethylene oxide)(PEO–PPO-PEO) block …

[HTML][HTML] Polymeric Mixed Micelle-Loaded Hydrogel for the Ocular Delivery of Fexofenadine for Treating Allergic Conjunctivitis

SA El-Shahed, DH Hassan, MA El-Nabarawi… - Polymers, 2024 - mdpi.com
This study was designed to formulate a polymeric mixed micelle (PMM) formulation to
sustainably release fexofenadine (FEX) to treat allergic conjunctivitis effectively. A 32 …

Micellar assembly leading to structural growth/transition in normal and reverse Tetronics® in single and mixed solution environment

D Patel, D Ray, VK Aswal, K Kuperkar, P Bahadur - Soft Matter, 2022 - pubs.rsc.org
This study scrutinizes the self-association of ethylene oxide (EO)-propylene oxide (PO)-
based star-shaped block copolymers as normal Tetronic®(T904) and reverse Tetronic® R …