[HTML][HTML] S100B's double life: intracellular regulator and extracellular signal

R Donato, G Sorci, F Riuzzi, C Arcuri, R Bianchi… - … et Biophysica Acta (BBA …, 2009 - Elsevier
The Ca2+-binding protein of the EF-hand type, S100B, exerts both intracellular and
extracellular functions. Recent studies have provided more detailed information concerning …

The S100B protein in biological fluids: more than a lifelong biomarker of brain distress

F Michetti, V Corvino, MC Geloso… - Journal of …, 2012 - Wiley Online Library
J. Neurochem.(2012) 120, 644–659. Abstract S100B is a calcium‐binding protein
concentrated in glial cells, although it has also been detected in definite extra‐neural cell …

Genetics of developmental dyslexia

TS Scerri, G Schulte-Körne - European child & adolescent psychiatry, 2010 - Springer
Developmental dyslexia is a highly heritable disorder with a prevalence of at least 5% in
school-aged children. Linkage studies have identified numerous loci throughout the genome …

S100B is increased in Parkinson's disease and ablation protects against MPTP-induced toxicity through the RAGE and TNF-α pathway

K Sathe, W Maetzler, JD Lang, RB Mounsey… - Brain, 2012 - academic.oup.com
Parkinson's disease is a neurodegenerative disorder that can, at least partly, be mimicked
by the neurotoxin 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine. S100B is a calcium …

S100B protein, a damage‐associated molecular pattern protein in the brain and heart, and beyond

G Sorci, R Bianchi, F Riuzzi, C Tubaro… - Cardiovascular …, 2010 - Wiley Online Library
S100B belongs to a multigenic family of Ca2+‐binding proteins of the EF‐hand type and is
expressed in high abundance in the brain. S100B interacts with target proteins within cells …

S100B protein in neurodegenerative disorders

J Steiner, B Bogerts, ML Schroeter… - Clinical Chemistry and …, 2011 - degruyter.com
Abstract “Classic” neurodegenerative disorders, such as Alzheimer's disease and
amyotrophic lateral sclerosis share common pathophysiological features and involve …

Schizophrenia and epilepsy: is there a shared susceptibility?

NG Cascella, DJ Schretlen, A Sawa - Neuroscience research, 2009 - Elsevier
Individuals with epilepsy are at increased risk of having psychotic symptoms that resemble
those of schizophrenia. More controversial and less searched is if schizophrenia is a risk …

Emerging role of S100B protein implication in Parkinson's disease pathogenesis

E Angelopoulou, YN Paudel, C Piperi - Cellular and Molecular Life …, 2021 - Springer
The exact etiology of Parkinson's disease (PD) remains obscure, lacking effective diagnostic
and prognostic biomarkers. In search of novel molecular factors that may contribute to PD …

Brain damage serum biomarkers induced by COVID-19 in patients from northeast Brazil

RC Silva, MM da Rosa, HI Leão, EDL Silva… - Journal of …, 2023 - Springer
Neurological symptoms have been often reported in COVID-19 disease. In the present
study, we evaluated brain damage associated with the increase of serum levels of …

Systematic review and meta-analysis of circulating S100B blood levels in schizophrenia

K Aleksovska, E Leoncini, S Bonassi, A Cesario… - PloS one, 2014 - journals.plos.org
S100B is a calcium-binding protein secreted in central nervous system from astrocytes and
other glia cells. High blood S100B levels have been linked to brain damage and psychiatric …