The introduction of duplex Doppler ultrasound almost half a century ago signified a
revolutionary advance in the ability to assess limb blood flow in humans. It is now widely …

Key points The concept of symmorphosis predicts that the capacity of each step of the
oxygen cascade is attuned to the task demanded of it during aerobic exercise at maximal …

Background Exercise intolerance is a hallmark symptom of heart failure patients with
preserved ejection fraction (HFpEF), which may be related to an impaired ability to …

An exaggerated blood pressure (BP) response to exercise has been linked to
cardiovascular disease, but little is known about the impact of age and sex on this response …

Although advanced robots can adeptly mimic human movement and aesthetics, they are still
unable to adapt or evolve in response to external experiences. To address this limitation, we …

The aims of this investigation were to describe the central alterations of neuromuscular
function induced by exhaustive high-intensity one-leg dynamic exercise (OLDE, study 1) and …

Obesity is now considered a primary comorbidity in heart failure with preserved ejection
fraction (HFpEF) pathophysiology, mediated largely by systemic inflammation. Although …

While vascular function, assessed as the ability of the vasculature to dilate in response to a
stimulus, is related to cardiovascular health, its relationship to exercise hyperemia is …

Although the contribution of noncardiac complications to the pathophysiology of heart failure
with preserved ejection fraction (HFpEF) have been increasingly recognized, disease …

Purpose We hypothesized exercise vasodilation would be greater in women due to nitric
oxide synthase (NOS) and cyclooxygenase (COX) signaling. Methods 45 healthy adults (23 …