Low molecular weight synthetic peptides have been demonstrated to be effective catalysts
for an increasingly wide array of asymmetric transformations. In many cases, these peptide …

Peptidomimetics represent an important field in chemistry, pharmacology and material
science as they circumvent the limitations of traditional peptides used in therapy. Self …

In the last decade, the field of sequence‐defined polymers and related ultraprecise,
monodisperse synthetic macromolecules has grown exponentially. In the early stage, mainly …

Polymer sequence programmability is required for the diverse structures and complex
properties that are achieved by native biological polymers, but efforts towards controlling the …

How did specific useful protein sequences arise from simpler molecules at the origin of life?
This seemingly needle-in-a-haystack problem has remarkably close resemblance to the old …

Structure-based design of synthetic inhibitors of protein–protein interactions (PPIs) requires
adept molecular design and synthesis strategies as well as knowledge of targetable …

This tutorial review examines recent developments involving use of Copper-catalyzed Azide-
Alkyne [3+ 2] Cycloaddition (CuAAC) reactions in the synthesis, modification, and …

A promising route to the synthesis of protein-mimetic materials that are capable of complex
functions, such as molecular recognition and catalysis, is provided by sequence-defined …

Peptoid oligomers were initially developed as part of a larger basic research effort to
accelerate the drug‐discovery process in the biotech/biopharma industry. Their ease of …

Peptoids, or oligomers of N-substituted glycines, are a class of foldamers that have shown
extraordinary functional potential since their inception nearly two decades ago. However …