Identification of inflammatory mediators and their modulation by strategies for the management of the systemic inflammatory response during cardiac surgery
R Hall - Journal of Cardiothoracic and Vascular Anesthesia, 2013 - jcvaonline.com
THE SYSTEMIC INFLAMMATORY RESPONSE (man-ifested by pyrexia, leukocytosis,
tachycardia, hypotension, tissue fluid accumulation, and organ failure) is generated during …
tachycardia, hypotension, tissue fluid accumulation, and organ failure) is generated during …
Strategies to attenuate maladaptive inflammatory response associated with cardiopulmonary bypass
Cardiopulmonary bypass (CPB) initiates an intense inflammatory response due to various
factors: conversion from pulsatile to laminar flow, cold cardioplegia, surgical trauma …
factors: conversion from pulsatile to laminar flow, cold cardioplegia, surgical trauma …
Impact of TNF-α (rs1800629) and IL-6 (rs1800795) Polymorphisms on Cognitive Impairment in Asian Breast Cancer Patients
Objective Expression of pro-inflammatory cytokines is influenced by single nucleotide
polymorphisms (SNPs) in the promoter regions of the pro-inflammatory cytokine genes, and …
polymorphisms (SNPs) in the promoter regions of the pro-inflammatory cytokine genes, and …
Blood cytokine expression correlates with early multi-organ damage in a mouse model of moderate hypothermia with circulatory arrest using cardiopulmonary bypass
Cardiopulmonary bypass (CPB) with moderate hypothermic cardiac arrest (MHCA) is
essential for prolonged complex procedures in cardiac surgery and is associated with …
essential for prolonged complex procedures in cardiac surgery and is associated with …
[HTML][HTML] Targeting the proinflammatory cytokine tumor necrosis factor-α to alleviate cardiopulmonary bypass-induced lung injury
M Gao, B Xie, C Gu, H Li… - Molecular Medicine …, 2015 - spandidos-publications.com
Pulmonary dysfunction is one of the most frequent complications associated with
cardiopulmonary bypass (CPB). Multiple factors, including the contact of blood with the …
cardiopulmonary bypass (CPB). Multiple factors, including the contact of blood with the …
Tumor necrosis factor-α–863 C/A promoter polymorphism affects the inflammatory response after cardiac surgery
J Boehm, K Hauner, J Grammer… - European Journal of …, 2011 - academic.oup.com
Objective: Cardiac surgery using cardiopulmonary bypass (CPB) initiates an inflammatory
response that shows a wide inter-individual range and determines postoperative morbidity …
response that shows a wide inter-individual range and determines postoperative morbidity …
[HTML][HTML] TNF-α-308G/A polymorphism associated with TNF-α protein expression in patients with diabetic nephropathy
Y Peng, LJ Li - International journal of clinical and experimental …, 2015 - ncbi.nlm.nih.gov
Aims: This study was to clarify the regulated effects of TNF-α-308G/A polymorphism on TNF-
α and investigate the relationship of-308G/A polymorphisms with diabetic nephropathy (DN) …
α and investigate the relationship of-308G/A polymorphisms with diabetic nephropathy (DN) …
Apolipoprotein E genotype, TNF-α 308G/A and risk for cardiac surgery associated-acute kidney injury in Caucasians
J Boehm, S Eichhorn, M Kornek, K Hauner… - Renal …, 2014 - Taylor & Francis
Objectives: Acute kidney injury following cardiac surgery depicts a severe clinical problem
that is strongly associated with adverse short-and long-term outcome. We analyzed two …
that is strongly associated with adverse short-and long-term outcome. We analyzed two …
Innate immune and neuronal genetic markers are highly predictive of postoperative pain and morphine patient-controlled analgesia requirements in Indian but not …
Objective Pain severity and opioid requirements in the postoperative period show
substantial and clinically significant inter-patient variation due mainly to factors such as age …
substantial and clinically significant inter-patient variation due mainly to factors such as age …
Association among 1267 A/G HSP70-2,− 308 G/A TNF-α polymorphisms and pro-inflammatory plasma mediators in old ZincAge population
R Giacconi, L Costarelli, M Malavolta, F Piacenza… - Biogerontology, 2014 - Springer
Proinflammatory cytokines and heat shock proteins play relevant roles in the pathogenesis
of inflammatory diseases. We investigated whether Hsp70 1267 A/G and TNF-α− 308 G/A …
of inflammatory diseases. We investigated whether Hsp70 1267 A/G and TNF-α− 308 G/A …