Chimeric antigen receptor (CAR) T cell therapies have demonstrated remarkable efficacy for
the treatment of hematological malignancies. However, in patients with solid tumors …

Immunotherapy with gene engineered CAR and TCR transgenic T-cells is a transformative
treatment in cancer medicine. There is a rich pipeline with target antigens and sophisticated …

Gut microbiota is essential for maintaining local and systemic immune homeostasis in the
presence of bacterial challenges. It has been demonstrated that microbiota play contrasting …

Cellular immunotherapy with chimeric antigen receptor (CAR)-T cells (CARTs) represents a
breakthrough in the treatment of hematologic malignancies. CARTs are genetically …

Cancer immunotherapy has witnessed a new renaissance with the advent of immune
checkpoint inhibitors, which reactivate T cells and foster endogenous anti-tumor responses …

During the last few years, the gut microbiota has gained increasing attention as a
consequence of its emerging role as a modulator of the immune system. With the advent of …

Gut microbiota composition influences the balance between human health and disease.
Increasing evidence suggests the involvement of microbial factors in regulating cancer …

Abnormal mutations in the microbial structure of early-weaning mammals are an important
cause of enteritis. Based on the multiple known beneficial functions of butyrate, we …

Cancer immunotherapy has entered the forefront of cancer treatment, but major challenges
still exist, such as the limited proportion of patients that respond to treatment and treatment …

The immune system plays a pivotal role in the battle against cancer, serving as a formidable
guardian in the ongoing fight against malignant cells. To combat these malignant cells …