The hypoxia signaling pathway is an evolutionarily conserved cellular signaling pathway
present in animals ranging from Caenorhabditis elegans to mammals. The pathway is …

Stress of aquatic animals occurs due to physical and physiological disturbances in the
aquatic environment or system when transportation, crowding, handling or changes of …

Dissolved oxygen (DO) is essential for the survival of aquatic organisms, while its absence
from water effectively compromises the health of fish in aquacultures. Here, we simulated …

Hypoxia and hyperoxia are disparate stressors which can have destructive influences on
fish growth and physiology. It is yet to be determined if hypoxia and hyperoxia have a …

Major progress has been made with genomic and genetic studies in aquaculture in the last
decade. However, research on epigenetic regulation of aquaculture traits is still at an early …

The decline in dissolved oxygen concentrations has been one of the most important
changes occurring in the oceans, greatly impacting the survival, abundance, development …

Hypoxia frequently occurs in natural aquatic systems and aquaculture environments due to
extreme climate fluctuations, high-density farming, environmental pollution and global …

The hypoxia-inducible transcription factors are key regulators for the physiological response
to low oxygen availability. In vertebrates, typically three Hif-α isoforms, Hif-1α, Hif-2α and Hif …

The hypoxia-inducible factor (HIF) pathway is a key regulator of cellular O2 homeostasis and
an important orchestrator of the physiological responses to hypoxia (low O2) in vertebrates …

Background information Heat stress in ectotherms involves direct (eg protein damage)
and/or indirect effects (temperature‐induced hypoxia and ROS formation), which cause …