COVID-19 and the role of cytokines in this disease

A Hasanvand - Inflammopharmacology, 2022 - Springer
Studies have shown that SARS-CoV-2 has the ability to activate and mature proinflammatory
cytokines in the body. Cytokine markers are a group of polypeptide signalling molecules that …

Exploring the contribution of pro-inflammatory cytokines to impaired wound healing in diabetes

S Nirenjen, J Narayanan, T Tamilanban… - Frontiers in …, 2023 - frontiersin.org
Background Impaired wound healing is the most common and significant complication of
Diabetes. While most other complications of Diabetes have better treatment options, diabetic …

The opportunistic nature of gut commensal microbiota

P Dey, S Ray Chaudhuri - Critical reviews in microbiology, 2023 - Taylor & Francis
The abundance of gut commensals has historically been associated with health-promoting
effects despite the fact that the definition of good or bad microbiota remains condition …

Targeting interleukin-17 enhances tumor response to immune checkpoint inhibitors in colorectal cancer

S Li, R Na, X Li, Y Zhang, T Zheng - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Although immune checkpoint inhibitors (ICIs) have gained much attention in managing
cancer, only a minority of patients, especially those with tumors that have been classified as …

Activation of mast cells by neuropeptides: the role of pro-inflammatory and anti-inflammatory cytokines

D Lauritano, F Mastrangelo, C D'Ovidio… - International journal of …, 2023 - mdpi.com
Mast cells (MCs) are tissue cells that are derived from bone marrow stem cells that
contribute to allergic reactions, inflammatory diseases, innate and adaptive immunity …

Interleukin‐25: New perspective and state‐of‐the‐art in cancer prognosis and treatment approaches

A Gowhari Shabgah, A Amir, ZR Gardanova… - Cancer …, 2021 - Wiley Online Library
Cancer is a leading cause of death which imposes a substantial financial burden. Among
the several mechanisms involved in cancer progression, imbalance of immune cell‐derived …

Interleukin‐17—A multifaceted cytokine in viral infections

U Sahu, D Biswas, VK Prajapati… - Journal of Cellular …, 2021 - Wiley Online Library
Viral infections are a major threat to the human population due to the lack of selective
therapeutic measures. The morbidity and mortality reported worldwide are very alarming …

The protective and pathogenic role of Th17 cell plasticity and function in the tumor microenvironment

Y Pan, W Yang, B Tang, X Wang, Q Zhang… - Frontiers in …, 2023 - frontiersin.org
At the turn of the century, researchers discovered a unique subtype of T helper cells that
secretes IL-17 and defined it as Th17. The latest study found that Th17 cells play both …

The double game played by Th17 cells in infection: host defense and immunopathology

M Paroli, R Caccavale, MT Fiorillo, L Spadea… - Pathogens, 2022 - mdpi.com
T-helper 17 (Th17) cells represent a subpopulation of CD4+ T lymphocytes that play an
essential role in defense against pathogens. Th17 cells are distinguished from Th1 and Th2 …

Interleukin-17 family cytokines in metabolic disorders and cancer

EV Meehan, K Wang - Genes, 2022 - mdpi.com
Interleukin-17 (IL-17) family cytokines are potent drivers of inflammatory responses.
Although IL-17 was originally identified as a cytokine that induces protective effects against …