Acid-sensing ion channel 3 (ASIC3) belongs to the epithelial sodium channel/degenerin
(ENaC/DEG) superfamily. There are 7 different ASIC subunits encoded by 5 different genes …

Advanced gene targeting technology and related tools in mice have been incorporated into
studies of acid-sensing ion channels (ASICs). A single ASIC subtype can be knocked out …

Acid-sensing ion channels (ASICs) are cation-permeable channels that in the periphery are
primarily expressed in sensory neurons that innervate tissues and organs. Soon after the …

Although acid‐sensing ion channels (ASICs) are proton‐gated ion channels responsible for
sensing tissue acidosis, accumulating evidence has shown that ASICs are also involved in …

The human ether-a-go-go-related gene KCNH2 encodes the voltage-gated potassium
channel underlying I Kr, a current critical for the repolarization phase of the cardiac action …

Neurons innervating the airways contribute to airway hyperreactivity (AHR), a hallmark
feature of asthma. Several observations suggested that acid-sensing ion channels (ASICs) …

In lumbar radiculopathy, the dorsal root or dorsal root ganglia (DRG) are compressed or
affected by herniated discs or degenerative spinal canal stenosis. The disease is multi …

Telemetric monitoring is used in many scientific fields, such as cardiovascular research,
neurology, endocrinology, as well as animal welfare research. Nowadays, implanted …

In peripheral artery disease (PAD), the metaboreceptor and mechanoreceptor in muscle
afferent nerves contribute to accentuated sympathetic outflow via a neural reflex termed …

Ventrikuläre Arrhythmien nehmen in der kardialen Forschung auf Grund ihrer hohen
Mortalitätsrate einen wichtigen Stellenwert ein. Die Maus dient dabei als wichtigstes …