Diabetes mellitus is characterized by insulin secretion from pancreatic β cells that is
insufficient to maintain blood glucose homeostasis. Autoimmune destruction of β cells …

Objective To evaluate current risk models and scores for type 2 diabetes and inform
selection and implementation of these in practice. Design Systematic review using standard …

Diabetes Mellitus (DM) is a metabolic disorder characterized by the presence of chronic
hyperglycemia either immune-mediated (Type 1 diabetes), insulin resistance (Type 2) …

Abstract" Serum ferritin" presents a paradox, as the iron storage protein ferritin is not
synthesised in serum yet is to be found there. Serum ferritin is also a well known …

We examined ranges of A1C useful for identifying persons at high risk for diabetes prior to
preventive intervention by conducting a systematic review. From 16 included studies, we …

Type 2 diabetes mellitus is an important preventable disease and a growing public health
problem. Epidemiologic and interventional studies suggest that weight loss is the main …

Abstract Background The World Health Organisation estimates that by 2030 there will be
approximately 350 million people with type 2 diabetes. Associated with renal complications …

Key Clinical Points Diagnosis of Diabetes Early screening and diagnosis allow for the
identification of at-risk persons (so that preventive measures, primarily lifestyle changes …

Trials have demonstrated the preventability of type 2 diabetes through lifestyle modifications
or drugs in people with impaired glucose tolerance. However, alternative ways of identifying …

Abstract Context: The Centers for Disease Control and Prevention estimates that there are
approximately 79,000,000 individuals in the United States with prediabetes [impaired …