Herpes simplex virus interference with immunity: Focus on dendritic cells

MA Farias, LF Duarte, EI Tognarelli, PA Gonzalez - Virulence, 2021 - Taylor & Francis
Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are highly prevalent in the human
population. These viruses cause lifelong infections by establishing latency in neurons and …

The modulatory role of dendritic cell-T cell cross-talk in breast cancer: Challenges and prospects

M Shahverdi, J Masoumi, F Ghorbaninezhad… - Advances in Medical …, 2022 - Elsevier
Antigen recognition and presentation are highlighted as the first steps in developing
specialized antigen responses. Dendritic cells (DCs) are outstanding professional antigen …

High CD26 and low CD94 expression identifies an IL-23 responsive Vδ2+ T cell subset with a MAIT cell-like transcriptional profile

KM Wragg, HX Tan, AB Kristensen… - Cell Reports, 2020 - cell.com
Vδ2+ T cells play a critical role in immunity to micro-organisms and cancer but exhibit
substantial heterogeneity in humans. Here, we demonstrate that CD26 and CD94 define …

Caveolin-1 regulates OMV-induced macrophage pro-inflammatory activation and multiple Toll-like receptors

A Sivanantham, W Alktaish, S Murugeasan… - Frontiers in …, 2023 - frontiersin.org
Macrophages (MФ), the primary cell of the innate immune system, serves as the first line of
defense. During bacterial infection, Gram-negative (G-) bacteria release nanosized outer …

Immunotherapeutic potential of mollusk hemocyanins in combination with human vaccine adjuvants in murine models of oral cancer

JJ Mora Román, M Del Campo, J Villar… - Journal of …, 2019 - Wiley Online Library
Mollusk hemocyanins have been used for decades in immunological and clinical
applications as natural, nontoxic, nonpathogenic, and nonspecific immunostimulants for the …

Caveolin-1 as a target in prevention and treatment of hypertrophic scarring

IL Kruglikov, PE Scherer - NPJ Regenerative Medicine, 2019 - nature.com
Reduced expression of caveolin-1 (Cav-1) is an important pathogenic factor in hypertrophic
scarring (HTS). Such a reduction can be found in connection with the main known risk …

New insights in the expression of stromal caveolin 1 in breast cancer spread to axillary lymph nodes

C Scatena, G Fanelli, GN Fanelli, M Menicagli… - Scientific reports, 2021 - nature.com
Recent evidence suggests that a loss of expression of caveolin in the stromal compartment
(sCav-1) of human invasive breast carcinoma (IBC) may be a predictor of disease …

AT2 receptor mediated activation of the tyrosine phosphatase PTP1B blocks caveolin-1 enhanced migration, invasion and metastasis of cancer cells

S Martínez-Meza, J Díaz, A Sandoval-Bórquez… - Cancers, 2019 - mdpi.com
The renin–angiotensin receptor AT2R controls systemic blood pressure and is also
suggested to modulate metastasis of cancer cells. However, in the latter case, the …

Caveolin-1 controls vesicular TLR2 expression, p38 signaling and T cell suppression in BCG infected murine monocytic myeloid-derived suppressor cells

V John, LA Kotze, E Ribechini, G Walzl… - Frontiers in …, 2019 - frontiersin.org
Monocytic myeloid-derived suppressor cells (M-MDSCs) and granulocytic MDSCs (G-
MDSCs) have been found to be massively induced in TB patients as well in murine Mtb …

Tropomodulin1 expression increases upon maturation in dendritic cells and promotes their maturation and immune functions

X Liu, X Xia, X Wang, J Zhou, LA Sung, J Long… - Frontiers in …, 2021 - frontiersin.org
Dendritic cells (DCs) are the most potent antigen-presenting cells. Upon maturation, DCs
express costimulatory molecules and migrate to the lymph nodes to present antigens to T …