Sirtuins are the class III of histone deacetylases whose deacetylate of histones is dependent
on nicotinamide adenine dinucleotide (NAD+). Among seven sirtuins, SIRT1 plays a critical …

Wide experimental evidence has been provided in the last decade concerning the
neuroprotective effects of phytochemicals in a variety of neurodegenerative disorders …

The cerebral ischemia injury can result in neuronal death and/or functional impairment,
which leads to further damage and dysfunction after recovery of blood supply. Cerebral …

Ischemic stroke is one of the leading causes of death, and even timely treatment can result
in severe disabilities. Reperfusion of the ischemic stroke region and restoration of the blood …

Although COVID-19 largely causes respiratory complications, it can also lead to various
extrapulmonary manifestations resulting in higher mortality and these comorbidities are …

Neuropathic pain results from lesions or diseases of the somatosensory nervous system and
it remains largely difficult to treat. Peripheral neuropathic pain originates from injury to the …

The scientific community, recently, has focused notable attention on the chemopreventive
and therapeutic effects of dietary polyphenols for human health. Emerging evidence …

Traumatic brain injury (TBI) is a shocking disease frequently followed by behavioral
disabilities, including risk of cerebral atrophy and dementia. N-formylpeptide receptor 1 …

The current pharmacological treatment for Parkinson's disease (PD) is focused on symptom
alleviation rather than disease prevention. In this study, we look at a new strategy to …

Diabetes mellitus (DM) is one of the principal manifestations of metabolic syndrome and its
prevalence with modern lifestyle is increasing incessantly. Chronic hyperglycemia can …