Clinical translation of nanomedicines: Challenges, opportunities, and keys

MA Younis, HM Tawfeek, AAH Abdellatif… - Advanced drug delivery …, 2022 - Elsevier
Despite the massive interest and recent developments in the field of nanomedicine, only a
limited number of formulations have found their way to the clinics. This shortcoming reveals …

Insights into active targeting of nanoparticles in drug delivery: advances in clinical studies and design considerations for cancer nanomedicine

AK Pearce, RK O'Reilly - Bioconjugate chemistry, 2019 - ACS Publications
Nanomedicine is a promising strategy for improving clinical outcomes for cancer therapies,
by improving drug efficacy through enhanced delivery to disease sites. It is of importance for …

Advanced nanomedicines for the treatment of inflammatory diseases

R Brusini, M Varna, P Couvreur - Advanced drug delivery reviews, 2020 - Elsevier
Inflammation, a common feature of many diseases, is an essential immune response that
enables survival and maintains tissue homeostasis. However, in some conditions, the …

Squalene-based multidrug nanoparticles for improved mitigation of uncontrolled inflammation in rodents

F Dormont, R Brusini, C Cailleau, F Reynaud… - Science …, 2020 - science.org
Uncontrolled inflammatory processes are at the root of numerous pathologies. Most recently,
studies on confirmed COVID-19 cases have suggested that mortality might be due to virally …

Evolution of nanomedicine formulations for targeted delivery and controlled release

S Puri, M Mazza, G Roy, RM England, L Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Nanotechnology research over the past several decades has been aimed primarily at
improving the physicochemical properties of small molecules to produce druggable …

Transition metal‐based therapies for inflammatory diseases

Y Song, Q You, X Chen - Advanced Materials, 2023 - Wiley Online Library
Inflammatory disease (ID) is a general term that covers all diseases in which chronic
inflammation performs as the major manifestation of pathogenesis. Traditional therapies …

Engineered nanomaterials for biomedical applications and their toxicity: a review

A Umapathi, M Kumawat, HK Daima - Environmental chemistry letters, 2022 - Springer
Nanotechnology has revolutionized the field of biomedical sciences with smart approaches
of imaging and treatment. This transformation has led to the development of a new field …

Current trends and challenges in pharmacoeconomic aspects of nanocarriers as drug delivery systems for cancer treatment

S Milewska, K Niemirowicz-Laskowska… - International journal …, 2021 - Taylor & Francis
Nanotherapy is a part of nanomedicine that involves nanoparticles as carriers to deliver
drugs to target locations. This novel targeting approach has been found to resolve various …

[HTML][HTML] Quality by design (QbD) in the formulation and optimization of liquid crystalline nanoparticles (LCNPs): A risk based industrial approach

T Waghule, N Dabholkar, S Gorantla, VK Rapalli… - Biomedicine & …, 2021 - Elsevier
The intersection of lipid-based nanoparticles and lyotropic liquid crystals has provided a
novel type of nanocarrier system known as 'lipid-based lyotropic liquid crystals' or 'liquid …

Ligand-based active targeting strategies for cancer theranostics

A Bandyopadhyay, T Das, S Nandy, S Sahib… - Naunyn-Schmiedeberg's …, 2023 - Springer
In the past decades, for the intermediate or advanced cancerous stages, preclinical and
clinical applications of nanomedicines in cancer theranostics have been extensively studied …