Piperidine derivatives: recent advances in synthesis and pharmacological applications

NA Frolov, AN Vereshchagin - International Journal of Molecular Sciences, 2023 - mdpi.com
Piperidines are among the most important synthetic fragments for designing drugs and play
a significant role in the pharmaceutical industry. Their derivatives are present in more than …

Exploring Guanidinium Organocatalysts for Hypoiodite‐Mediated Reactions

M Odagi, K Nagasawa - The Chemical Record, 2023 - Wiley Online Library
This account describes our recent work on developing guanidinium hypoiodite‐catalysts for
oxidative carbon‐nitrogen and carbon‐carbon bond‐forming reactions. These reactions …

Enantioselective Oxidative Enolate Coupling of Oxindoles Catalyzed by Chiral Guanidinium Hypoiodite

M Odagi, I Mori, K Sugimoto, K Nagasawa - ACS Catalysis, 2023 - ACS Publications
Hypoiodite is an environmentally friendly oxidant that has been developed to drive a variety
of bond-forming reactions. Recently, asymmetric oxidative bond-forming reactions using …

Chirality memory of α-methylene-π-allyl iridium species

Y Cui, Y Zhai, J Xiao, C Li, WF Zheng, C Huang… - Chemical …, 2021 - pubs.rsc.org
Chirality is one of the most important types of steric information in nature. In addition to
central chirality, axial chirality has been catching more and more attention from scientists …

Oxovanadium (v)-catalyzed oxidative cross-coupling of enolates using O 2 as a terminal oxidant

Y Osafune, Y Jin, T Hirao, M Tobisu… - Chemical …, 2020 - pubs.rsc.org
The oxovanadium (V)-catalyzed oxidative cross-coupling of enolates using O2 as a terminal
oxidant is reported, where a boron enolate and a silyl enol ether were employed as …

Asymmetric Total Synthesis and Structure Elucidation of Huperzine H

S Shiomi, K Wilailak, W Soutome… - The Journal of …, 2022 - ACS Publications
A first asymmetric total synthesis of huperzine H has been achieved in a 12% overall yield
from commercially available (+)-pulegone. The key steps of this synthesis include a highly …

Recent advances in the oxidative coupling reaction of enol derivatives

C Wei, L Qiang - Chinese Journal of Organic Chemistry, 2021 - sioc-journal.cn
Oxidative coupling reaction of enol derivatives (enolates, enol silanes, enamines, etc.)
provides an efficient method for the direct construction of carbon-carbon bond, which plays a …

K 2 S 2 O 8-promoted C–Se bond formation to construct α-phenylseleno carbonyl compounds and α, β-unsaturated carbonyl compounds

XY Yang, R Wang, L Wang, J Li, S Mao, SQ Zhang… - RSC …, 2020 - pubs.rsc.org
A novel K2S2O8-promoted C–Se bond formation from cross-coupling under neutral
conditions has been developed. A variety of aldehydes and ketones react well using …

Fluorescent sensors for Water

Y Ooyama - 2022 - books.rsc.org
The detection and quantification of water in solutions, solids, and gases or water on
materials surface are doubtlessly significant in not only organic and analytical chemistry but …

烯醇类化合物氧化偶联反应研究进展

陈伟, 刘强 - 有机化学, 2021 - sioc-journal.cn
摘要烯醇类化合物氧化偶联反应作为直接构建C—C 键的高效合成方法之一,
是有机化学领域研究关注的重点. 尽管首例烯醇类化合物氧化偶联反应早在1935 年就已被报道 …