Lipid droplets are cytosolic fat storage organelles present in most eukaryotic cells. Long
regarded merely as inert fat reservoirs, they are now emerging as major regulators of …

Cancer cells possess remarkable abilities to adapt to adverse environmental conditions.
Their survival during severe nutrient and oxidative stress depends on their capacity to …

The functional state of T cells is a key determinant for effective antitumor immunity and
immunotherapy. Cellular metabolism, including lipid metabolism, controls T cell …

Lipid droplets (LDs) provide an" on-demand" source of fatty acids (FAs) that can be
mobilized in response to fluctuations in nutrient abundance. Surprisingly, the amount of LDs …

Lipid droplets are intracellular organelles that are found in most cells, where they have
fundamental roles in metabolism. They function prominently in storing oil-based reserves of …

Lipid droplet (LD) accumulation is a now well-recognised hallmark of cancer. However, the
significance of LD accumulation in colorectal cancer (CRC) biology is incompletely …

Among organelles, lipid droplets (LDs) uniquely constitute a hydrophobic phase in the
aqueous environment of the cytosol. Their hydrophobic core of neutral lipids stores …

Cytoplasmic lipid droplets are important organelles in nearly every eukaryotic and some
prokaryotic cells. Storing and providing energy is their main function, but they do not work in …

Much has been made about JLW Thudichum's colorful, and one could say clairvoyant,
naming of sphingosine “in commemoration of the many enigmas which it presented to the …

Lipid droplets (LDs) are independent organelles that are composed of a lipid ester core and
a surface phospholipid monolayer. Recent studies have revealed many new proteins …